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引用本文的文献

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An overview of contemporary theories of ageing.当代衰老理论综述。
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Telomere shortening in T cells correlates with Alzheimer's disease status.T细胞中的端粒缩短与阿尔茨海默病状态相关。
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Is human immunosenescence clinically relevant? Looking for 'immunological risk phenotypes'.人类免疫衰老与临床相关吗?寻找“免疫风险表型”。
Trends Immunol. 2002 Jul;23(7):330-2. doi: 10.1016/s1471-4906(02)02255-x.
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罗伊·瓦尔福德与衰老的免疫学理论。

Roy Walford and the immunologic theory of aging.

作者信息

Effros Rita B

机构信息

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA Los Angeles, CA 90024, USA.

出版信息

Immun Ageing. 2005 Apr 25;2(1):7. doi: 10.1186/1742-4933-2-7.

DOI:10.1186/1742-4933-2-7
PMID:15850487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1131916/
Abstract

Roy Walford died on April 27, 2004, at the age of 79. His contributions to gerontological research in such diverse areas as caloric restriction, genetics of lifespan, immunosenescence, DNA repair and replicative senescence were truly remarkable in their depth and innovation. Significantly, most of the areas that he pioneered during his illustrious research career remain the "hot" areas of current gerontological research. In this sense, he has achieved the most important type of immortality. His death was a major personal and professional loss to numerous scientists within the gerontological community. In launching this new journal on Immunity and Ageing, it is highly fitting, therefore, to remember him on the anniversary of his death by briefly reviewing the contributions of Roy Walford to this important facet of gerontology. Indeed, it was Roy who actually first coined the commonly used term "immunosenescence".

摘要

罗伊·沃尔福德于2004年4月27日去世,享年79岁。他在热量限制、寿命遗传学、免疫衰老、DNA修复和复制性衰老等多个不同领域对老年学研究做出的贡献,在深度和创新性方面都堪称卓越。值得注意的是,他在辉煌的研究生涯中开创的大多数领域,至今仍是当前老年学研究的“热门”领域。从这个意义上说,他实现了最重要的一种不朽。他的离世对老年学领域的众多科学家来说,是个人和专业上的重大损失。因此,在这本关于《免疫与衰老》的新期刊创刊之际,在他逝世周年纪念日通过简要回顾罗伊·沃尔福德对老年学这一重要方面的贡献来缅怀他,是非常合适的。事实上,正是罗伊首次创造了常用术语“免疫衰老”。