Vella Cecil, Grech Victor
Paediatric Department, St Luke's Hospital, Guardamangia, Malta.
Pediatr Allergy Immunol. 2005 May;16(3):258-61. doi: 10.1111/j.1399-3038.2005.00253.x.
In the treatment of bronchial asthma, inhaled therapy with both bronchodilators and corticosteroids represents the basis for acute and long-term management. Drug therapy in asthma is predominantly by pressurized metered dose inhalers. The impact of treatment on the disease morbidity and mortality depends to a large extent on appropriate delivery of drug to the lungs by means of a spacer device. We performed an audit on spacer use in 200 children and showed that 99% owned a spacer, 2% owned but did not use their spacer, 11% were using a spacer which was not ideal for their age, 17% had a poor technique, and 24% were not following the recommendations given on previous visits to wash the spacer only with a soapy solution. Although physicians frequently associate poor control of asthma with inadequate doses of drugs, many factors must be considered before increasing the dose of inhaled medications to children. We should all ensure that the drugs we prescribe are delivered in the best possible manner, thus improving control of asthma, reducing side effects and offering a more cost-effective therapy.
在支气管哮喘的治疗中,使用支气管扩张剂和皮质类固醇进行吸入治疗是急性和长期管理的基础。哮喘的药物治疗主要通过压力定量吸入器进行。治疗对疾病发病率和死亡率的影响在很大程度上取决于通过储雾罐装置将药物适当地输送到肺部。我们对200名儿童使用储雾罐的情况进行了一次审查,结果显示,99%的儿童拥有储雾罐,2%的儿童拥有但未使用储雾罐,11%的儿童使用的储雾罐对其年龄不合适,17%的儿童使用技术不佳,24%的儿童未遵循之前就诊时给出的仅用肥皂溶液清洗储雾罐的建议。尽管医生经常将哮喘控制不佳与药物剂量不足联系起来,但在给儿童增加吸入药物剂量之前,必须考虑许多因素。我们都应该确保我们所开的药物以尽可能最佳的方式输送,从而改善哮喘控制、减少副作用并提供更具成本效益的治疗。