Ramirez Francisco C, Shaukat Masud S, Young Michele A, Johnson David A, Akins Rodney
Gastroenterology Section, Department of Medicine, Carl T. Hayden Veterans Affairs Medical Center, Phoenix, AZ 85012, USA.
Gastrointest Endosc. 2005 May;61(6):741-6. doi: 10.1016/s0016-5107(05)00322-6.
Capsule endoscopy is a major technological advancement in the visualization of the small bowell. Its utility in the evaluation of the esophagus is mainly limited by its rapid and unpredictable transmission, thus limiting the number of pictures of the esophagus, in particular, the distal esophagus.
Strings were attached to the wireless capsule endoscopy device to allow its controlled movement up and down the esophagus. Microbiologic cultures of the capsule's surface after high-level disinfection were carried out after the procedure. At the time of recording, discomfort associated with the procedure was documented. Patient preference compared with conventional EGD was recorded. An independent endoscopist blinded to the EGD diagnoses assessed the diagnostic accuracy of pictures obtained.
Fifty patients with Barrett's esophagus were enrolled: 28 with short-segment Barrett's and 22 with long-segment Barrett's. The procedure was safe (no strings were disrupted, and no capsule was lost), and it rendered negative microbiologic cultures after high-level disinfection. The mean recording time was 7.9 minutes; all patients with both short- and long-segment Barrett's esophagus were successfully identified. The difficulty/discomfort associated with swallowing the device, throat discomfort, gagging, moving the capsule (up and down and upon retrieval of the capsule) was none or minimal in 74%, 98%, 96%, 94%, and 76%, respectively. A single capsule was used in 24 studies, and the majority of patients (92%) preferred string-capsule endoscopy to EGD.
String-capsule endoscopy was feasible, safe, and highly acceptable, and was preferred by patients and may prove to be more cost effective than screening EGD.
胶囊内镜是小肠可视化检查中的一项重大技术进步。其在食管评估中的应用主要受其快速且不可预测的传输限制，从而限制了食管图像数量，尤其是食管远端的图像数量。
将线绳连接到无线胶囊内镜设备上，以便在食管内上下控制其移动。术后对经过高水平消毒的胶囊表面进行微生物培养。记录过程中，记录与该操作相关的不适情况。记录患者与传统上消化道内镜检查（EGD）相比的偏好。一位对EGD诊断不知情的独立内镜医师评估所获得图像的诊断准确性。
纳入了50例巴雷特食管患者：28例为短节段巴雷特食管，22例为长节段巴雷特食管。该操作安全（线绳未中断，胶囊未丢失），且在高水平消毒后微生物培养结果为阴性。平均记录时间为7.9分钟；所有短节段和长节段巴雷特食管患者均被成功识别。吞咽设备相关的困难/不适、咽喉不适、恶心、移动胶囊（上下移动及取出胶囊时）在74%、98%、96%、94%和76%的患者中分别为无或轻微。24项研究中使用了单个胶囊，大多数患者（92%）更喜欢线绳-胶囊内镜检查而非EGD。
线绳-胶囊内镜检查可行、安全且高度可接受，患者更倾向于选择，并且可能比筛查性EGD更具成本效益。
