Liao Zhuan, Gao Rui, Xu Can, Xu Dan-Feng, Li Zhao-Shen
Department of Gastroenterology, Digestive Endoscopy Center, Changhai Hospital, Second Military Medicine University, Shanghai, China.
Gastrointest Endosc. 2009 Aug;70(2):201-9. doi: 10.1016/j.gie.2008.10.043. Epub 2009 Mar 14.
Previous studies suggest that string capsule endoscopy is feasible, safe, accurate, highly acceptable, and likely to be proven as a more cost-effective technique than conventional EGD. However, this technique needs proper high-level disinfection, and the string attachment is not easy to perform. We developed a modified esophageal capsule endoscopy, called sleeve string capsule endoscopy (SSCE).
To assess the feasibility and safety of SSCE in the evaluation of esophageal diseases.
A pilot study.
Outpatient setting in a tertiary hospital, Shanghai, China.
Two healthy volunteers and 8 patients with suspected esophageal diseases were enrolled.
The OMOM capsule endoscope was enclosed in a small, transparent, thin, latex sleeve, with a string attached to the caudal end. Both the sleeve and the string were for single use and were discarded after completion of the procedure. Two healthy volunteers without previous EGD and 8 patients who had undergone EGD swallowed the capsules. Pictures of the esophagus were viewed in real time.
Discomfort associated with the procedure, quality, and diagnostic value of the pictures were documented. In addition, patient preference between SSCE and conventional EGD was recorded.
SSCE was successfully carried out in the 10 subjects. The procedures were easy and safe to perform. No sleeves and strings were disrupted or broken, and no capsule was lost. The mean overall discomfort score during SSCE in the 8 patients was 2.88 (range 2-5). Pictures generated during SSCE were generally of high quality and produced identical diagnoses to those obtained by EGD in all 8 patients. In addition, all the 8 patients preferred SSCE to EGD.
This was a single-center nonrandomized study with a small sample size.
SSCE was a feasible, easy-to-operate, and safe method for the diagnosis of esophageal diseases without the need for disinfection. SSCE appears to possess the same diagnostic capacity as that of EGD.
先前的研究表明，线阵胶囊内镜是可行、安全、准确、高度可接受的，并且可能被证明是一种比传统上消化道内镜检查更具成本效益的技术。然而，这项技术需要适当的高水平消毒，并且线的附着操作并不容易。我们开发了一种改良的食管胶囊内镜，称为袖套线阵胶囊内镜（SSCE）。
评估SSCE在食管疾病评估中的可行性和安全性。
一项前瞻性研究。
中国上海一家三级医院的门诊。
招募了2名健康志愿者和8名疑似食管疾病患者。
将OMOM胶囊内镜封装在一个小的、透明的、薄的乳胶袖套中，在尾端连接一根线。袖套和线均为一次性使用，检查完成后丢弃。2名未曾接受过上消化道内镜检查的健康志愿者和8名接受过上消化道内镜检查的患者吞下了胶囊。实时查看食管的图像。
记录与检查相关的不适、图像质量和诊断价值。此外，记录患者对SSCE和传统上消化道内镜检查的偏好。
10名受试者均成功进行了SSCE。操作简便且安全。没有袖套和线被破坏或断裂，也没有胶囊丢失。8名患者在SSCE过程中的总体不适评分平均为2.88（范围为2 - 5）。SSCE过程中生成的图像质量普遍较高，在所有8名患者中得出的诊断结果与上消化道内镜检查相同。此外，所有8名患者更喜欢SSCE而非上消化道内镜检查。
这是一项单中心、非随机、小样本量的研究。
SSCE是一种可行、易于操作且安全的食管疾病诊断方法，无需消毒。SSCE似乎具有与上消化道内镜检查相同的诊断能力。
