从西方水杨梅的根和茎皮中分离得到的六种新三萜皂苷。

Six new triterpenoid saponins from the root and stem bark of Cephalanthus occidentalis.

作者信息

Zhang Zhizhen, Li Shiyou, Zhang Shanmin

机构信息

Center for Medicinal Plant Research, Arthur Temple College of Forestry, Stephen F. Austin State University, Nacogdoches, Texas 75962-6109, USA.

出版信息

Planta Med. 2005 Apr;71(4):355-61. doi: 10.1055/s-2005-864103.

DOI:10.1055/s-2005-864103

PMID:15856414

Abstract

From the root and stem bark of Cephalanthus occidentalis L., a common American wetland species, six new triterpenoid saponins (1 - 6), together with 29 known compounds were isolated and identified. On the basis of spectroscopic analysis and chemical degradation, the structures of new compounds were elucidated as 3-O-beta-glucopyranosylcincholic acid (1), cincholic acid 28-O-beta-glucopyranosyl ester (2), 3-O-beta-glucopyranosyl-(1-->4)-beta-fucopyranosylcincholic acid (3), 3-O-beta-glucopyranosyl-(1-->4)-beta-fucopyranosylcincholic acid 28-O-beta-glucopyranosyl ester (4), 3-O-beta-glucopyranosylcincholic acid 28-O-alpha-arabinopyranosyl-(1-->2)-beta-glucopyranosyl ester (5), and 3-O-beta-glucopyranosylquinovic acid 28-O-alpha-arabinopyranosyl-(1-->2)-beta-glucopyranosyl ester (6).

摘要

从美洲常见湿地物种西方水杨梅（Cephalanthus occidentalis L.）的根和茎皮中，分离并鉴定出六种新的三萜皂苷（1 - 6）以及29种已知化合物。基于光谱分析和化学降解，新化合物的结构被阐明为3 - O - β - 吡喃葡萄糖基金鸡纳酸（1）、金鸡纳酸28 - O - β - 吡喃葡萄糖基酯（2）、3 - O - β - 吡喃葡萄糖基 - （1→4） - β - 岩藻糖基金鸡纳酸（3）、3 - O - β - 吡喃葡萄糖基 - （1→4） - β - 岩藻糖基金鸡纳酸28 - O - β - 吡喃葡萄糖基酯（4）、3 - O - β - 吡喃葡萄糖基金鸡纳酸28 - O - α - 阿拉伯吡喃糖基 - （1→2） - β - 吡喃葡萄糖基酯（5）和3 - O - β - 吡喃葡萄糖基奎诺酸28 - O - α - 阿拉伯吡喃糖基 - （1→2） - β - 吡喃葡萄糖基酯（6）。