Huter O, Brezinka C, Sölder E, Kölle D, Drexel H
Universitätsklinik für Frauenheilkunde, Universitätsklinik für Innere Medizin Innsbruck.
Zentralbl Gynakol. 1992;114(1):18-24.
After birth of an infant with a birthweight of 4000 g or more maternal glucose tolerance should be examined. We measured blood glucose values after a 100 g oral glucose challenge and compared them with serum fructosamine values of the same subjects. 40 women who had given birth to an infant with macrosomia (group I) were matched with 40 women who had delivered babies with normal birthweight (group II). Impaired glucose tolerance was found in 6 women (15%) of group I, and in one woman (2.5%) of group II. Fructosamine values were within the normal range in each of the seven women (1.74 + 0.2 mmol/l vs 1.73 + 0.2 mmol/l). Thus, fructosamine determination is not sensitive enough to detect impaired glucose tolerance in asymptomatic women post partum. It is not feasible to replace the oral glucose tolerance test in screening for gestational diabetes mellitus.
出生体重达到或超过4000克的婴儿出生后，应检查母亲的糖耐量。我们在口服100克葡萄糖后测量血糖值，并将其与同一受试者的血清果糖胺值进行比较。40名分娩巨大儿的妇女（第一组）与40名分娩正常体重婴儿的妇女（第二组）进行匹配。第一组中有6名妇女（15%）糖耐量受损，第二组中有1名妇女（2.5%）糖耐量受损。7名妇女的果糖胺值均在正常范围内（1.74±0.2毫摩尔/升对1.73±0.2毫摩尔/升）。因此，测定果糖胺对检测产后无症状妇女的糖耐量受损不够敏感。在筛查妊娠期糖尿病时，用果糖胺测定取代口服葡萄糖耐量试验是不可行的。
