Poulose V, Chiam P, Poh W T
Department of Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889.
Singapore Med J. 2005 May;46(5):229-32.
Kikuchi's disease is a benign form of cervical lymphadenopathy that commonly affects young adults. We report a case series from our hospital.
The clinical features of 23 cases of Kikuchi's disease diagnosed at Changi General Hospital over a seven year period are presented. The cases were identified from pathology records using the search term histiocytic necrotising lymphadenitis.
Most of our patients (78 percent) were young women who presented with cervical lymphadenopathy. The median age was 31 years. In the 18 cases who completed follow-up at the hospital, there was spontaneous resolution of symptoms within a six-month period. One patient demonstrated seropositivity for systemic lupus erythematosus (SLE) and was initially started on steroids. However, the treatment was discontinued shortly afterwards since she did not meet the diagnostic criteria for SLE. Excision biopsy of the affected lymph node was the diagnostic method of choice.
Kikuchi's disease is not uncommon in the Singaporean population. Establishing an early diagnosis is crucial since the clinical presentation can mimic tuberculous lymphadenitis or malignant lymphoma. The diagnostic method of choice is excision biopsy.
菊池病是一种良性颈部淋巴结病，常见于年轻人。我们报告我院的一组病例。
介绍了新加坡樟宜综合医院七年间诊断的23例菊池病的临床特征。通过使用搜索词“组织细胞坏死性淋巴结炎”从病理记录中识别出这些病例。
我们的大多数患者（78%）为年轻女性，表现为颈部淋巴结病。中位年龄为31岁。在18例在我院完成随访的患者中，症状在六个月内自行缓解。一名患者系统性红斑狼疮（SLE）血清学呈阳性，最初开始使用类固醇治疗。然而，由于她不符合SLE的诊断标准，治疗不久后就停止了。受影响淋巴结的切除活检是首选的诊断方法。
菊池病在新加坡人群中并不罕见。由于临床表现可能类似于结核性淋巴结炎或恶性淋巴瘤，早期诊断至关重要。首选的诊断方法是切除活检。
