Martínez-Vázquez C A, Bordón J, Rubianes M, De la Fuente J, Sopeña B, Macías M, López-Guerra N
Unidad de Enfermedades Infecciosas, Hospital Xeral, Vigo.
An Med Interna. 1998 Jul;15(7):367-9.
We had reviewed all the patients with Histiocytic Necrotizing Lymphadenitis (Kikuchi's disease) seen in a General Hospital during two years. Three of the six cases were young females who showed the same clinical symptoms: Fever and unilateral painful, lymphadenopathy, usually at the latero-cervical region. All patients have mild neutropenia and high levels of serum transaminases. The lymph node biopsy yielded the proper diagnostic in all cases. The course of disease was good, and all patients healed without treatment one to two month after the symptom started. To date, we have not recorded any relapse. Our finding are quite similar to the other cases published in the medical literature. The benign course of this disease, and the need for biopsy to get a correct diagnosis, can explain why this disease may be unrecognized in clinical practice.
我们回顾了一家综合医院在两年内收治的所有组织细胞坏死性淋巴结炎（菊池病）患者。6例患者中有3例为年轻女性，表现出相同的临床症状：发热、单侧疼痛性淋巴结病，通常位于颈外侧区。所有患者均有轻度中性粒细胞减少和血清转氨酶水平升高。所有病例经淋巴结活检均得以确诊。疾病过程良好，所有患者在症状出现后1至2个月未经治疗即痊愈。迄今为止，我们尚未记录到任何复发情况。我们的发现与医学文献中发表的其他病例非常相似。这种疾病的良性病程以及需要活检才能获得正确诊断，这可以解释为什么在临床实践中这种疾病可能未被识别。
