用丹曲林钠治疗不明原因的术后高热。
Postoperative hyperthermia of unknown origin treated with dantrolene sodium.
作者信息
Inada Hirohito, Jinno Shigeharu, Kohase Hikaru, Fukayama Haruhisa, Umino Masahiro
机构信息
Section of Anesthesiology and Clinical Physiology, Department of Oral Restitution, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
出版信息
Anesth Prog. 2005 Spring;52(1):21-3. doi: 10.2344/0003-3006(2005)52[21:PHOUOT]2.0.CO;2.
An 11-year-old girl was scheduled for alveolar cleft bone grafting with an iliac bone under general anesthesia. Anesthesia was performed with 70% nitrous oxide, 30% oxygen, and propofol. On the first and second postoperative day, persistent hyperthermia was observed. Because the administration of diclofenac sodium had not been effective for the hyperthermia, dantrolene sodium was given. Her body temperature gradually dropped and returned to normal level on the fifth postoperative day. The hyperthermia in the present case might have been caused by a rapidly elevated muscle metabolism in response to pain and stress after the propofol anesthesia. The oral administration of dantrolene sodium successfully lowered the patient's high body temperature.
一名11岁女孩计划在全身麻醉下用髂骨进行牙槽嵴裂植骨术。麻醉采用70%氧化亚氮、30%氧气和丙泊酚。术后第一天和第二天，观察到持续高热。由于双氯芬酸钠对高热无效，给予了丹曲林钠。她的体温逐渐下降，在术后第五天恢复到正常水平。本例中的高热可能是由于丙泊酚麻醉后因疼痛和应激导致肌肉代谢迅速升高所致。口服丹曲林钠成功降低了患者的高热体温。
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