Guntani Atsushi, Yoshiga Ryosuke, Mii Shinsuke
Department of Vascular Surgery, Saiseikai Yahata General Hospital, 5-9-27 Haruno-machi, Yahatahigashi-ku, Kitakyushu, 805-8527, Japan.
Surg Case Rep. 2020 Jul 31;6(1):188. doi: 10.1186/s40792-020-00946-2.
Propofol infusion syndrome (PRIS) is a rare but potentially lethal side effect during propofol administration.
The patient was scheduled for abdominal aortic aneurysm resection and reconstruction. Propofol used during sedation for ventilation after the surgery-induced rhabdomyolysis, heart failure, and renal failure. Discontinuation of propofol administration led to a dramatic improvement in the fatal symptoms, resulting in a diagnosis of PRIS.
We herein report a rare case of a PRIS during sedation in the intensive care unit after abdominal aortic aneurysm surgery. Physicians using propofol should therefore be aware of the potential risk of PRIS.
丙泊酚输注综合征（PRIS）是丙泊酚给药过程中一种罕见但可能致命的副作用。
该患者计划进行腹主动脉瘤切除和重建手术。术后镇静通气期间使用的丙泊酚引发了横纹肌溶解、心力衰竭和肾衰竭。停用丙泊酚给药后，致命症状显著改善，从而确诊为PRIS。
我们在此报告一例腹主动脉瘤手术后重症监护病房镇静期间发生PRIS的罕见病例。因此，使用丙泊酚的医生应意识到PRIS的潜在风险。
