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一例腹主动脉瘤手术后疑似丙泊酚输注综合征的病例。

A case of suspected propofol infusion syndrome after abdominal aortic aneurysm surgery.

作者信息

Guntani Atsushi, Yoshiga Ryosuke, Mii Shinsuke

机构信息

Department of Vascular Surgery, Saiseikai Yahata General Hospital, 5-9-27 Haruno-machi, Yahatahigashi-ku, Kitakyushu, 805-8527, Japan.

出版信息

Surg Case Rep. 2020 Jul 31;6(1):188. doi: 10.1186/s40792-020-00946-2.

Abstract

BACKGROUND

Propofol infusion syndrome (PRIS) is a rare but potentially lethal side effect during propofol administration.

CASE PRESENTATION

The patient was scheduled for abdominal aortic aneurysm resection and reconstruction. Propofol used during sedation for ventilation after the surgery-induced rhabdomyolysis, heart failure, and renal failure. Discontinuation of propofol administration led to a dramatic improvement in the fatal symptoms, resulting in a diagnosis of PRIS.

CONCLUSIONS

We herein report a rare case of a PRIS during sedation in the intensive care unit after abdominal aortic aneurysm surgery. Physicians using propofol should therefore be aware of the potential risk of PRIS.

摘要

背景

丙泊酚输注综合征(PRIS)是丙泊酚给药过程中一种罕见但可能致命的副作用。

病例报告

该患者计划进行腹主动脉瘤切除和重建手术。术后镇静通气期间使用的丙泊酚引发了横纹肌溶解、心力衰竭和肾衰竭。停用丙泊酚给药后,致命症状显著改善,从而确诊为PRIS。

结论

我们在此报告一例腹主动脉瘤手术后重症监护病房镇静期间发生PRIS的罕见病例。因此,使用丙泊酚的医生应意识到PRIS的潜在风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4a3/7394992/16ec2ccd19d1/40792_2020_946_Fig1_HTML.jpg

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