Baker Susan, Barlow Sarah, Cochran William, Fuchs George, Klish William, Krebs Nancy, Strauss Richard, Tershakovec Andrew, Udall John
J Pediatr Gastroenterol Nutr. 2005 May;40(5):533-43. doi: 10.1097/01.mpg.0000161147.16590.12.
Childhood overweight and obesity are major health problems with immediate and long-term consequences of staggering magnitude. Despite this, there are few preventive and therapeutic strategies of proven effectiveness available to public health and clinical practitioners. Accruing such evidence is currently and appropriately a health policy priority, but there is an urgent need to intervene even before comprehensive solutions are fully established. The aim of this Clinical Report on Overweight Children and Adolescents is to present information on current understanding of pathogenesis and treatment of overweight and obesity. We report on the epidemiology, molecular biology and medical conditions associated with overweight; on dietary, exercise, behavioral, pharmacological and surgical treatments; and on the primary prevention of overweight in children and adolescents.
儿童超重和肥胖是重大健康问题,会产生规模惊人的近期和长期后果。尽管如此,公共卫生和临床从业者可采用的经证实有效的预防和治疗策略却很少。积累此类证据目前恰是一项卫生政策重点,但即便在全面解决方案完全确立之前,也迫切需要进行干预。这份关于超重儿童和青少年的临床报告旨在介绍有关超重和肥胖发病机制及治疗的当前认识。我们报告了与超重相关的流行病学、分子生物学和医学状况;饮食、运动、行为、药物和手术治疗;以及儿童和青少年超重的一级预防。