Herrmann Wolfgang Artur, Lohmann Chris Patrick, Demmler-Hackenberg Martina, Gabel Veit-Peter
University Eye Clinic, University of Regensburg, Franz-Josef-Strauss Allee 11, 93042, Regensburg, Germany.
Graefes Arch Clin Exp Ophthalmol. 2005 Apr;243(4):383-5. doi: 10.1007/s00417-004-0999-3. Epub 2004 Oct 13.
Young patients with vitreous, retinal and subvitreal haemorrhages without neovascularisation or prior trauma are a diagnostic challenge for the physician. In this case report, a patient is presented who developed unilateral, spontaneous, subvitreal, retinal and subretinal haemorrhages and was diagnosed with von Willebrand's disease.
A 33-year-old Caucasian woman presented at our clinic with unilateral subvitreal, retinal and subretinal haemorrhages. The haemorrhages occurred spontaneously without prior trauma, and the patient had no history of prior bleeding complications. Analysis of the coagulation-fibrinolysis system and von Willebrand multimer analysis led to the diagnosis von Willebrand's disease type I.
Spontaneous subvitreal, retinal and subretinal haemorrhages may be associated with coagulation disorders. Especially in young patients, von Willebrand's disease should be considered as a possible cause.
对于年轻患者，若出现玻璃体、视网膜及玻璃体下出血，且无新生血管形成或既往外伤史，这对医生来说是一个诊断难题。在本病例报告中，呈现了一名出现单侧、自发性玻璃体下、视网膜及视网膜下出血并被诊断为血管性血友病的患者。
一名33岁的白种女性因单侧玻璃体下、视网膜及视网膜下出血前来我院就诊。出血为自发性，无既往外伤史，且患者无既往出血并发症史。凝血 - 纤溶系统分析及血管性血友病多聚体分析确诊为Ⅰ型血管性血友病。
自发性玻璃体下、视网膜及视网膜下出血可能与凝血障碍有关。尤其是年轻患者，应考虑血管性血友病为可能病因。
