Steigrad Stephen, Hacker Neville F, Kolb Bradford
Department of Reproductive Medicine, Royal Hospital for Women, Randwick NSW, Australia.
Fertil Steril. 2005 May;83(5):1547-9. doi: 10.1016/j.fertnstert.2005.01.093.
To describe an IVF surrogate pregnancy from a patient who had a radical hysterectomy followed by excision of a laparoscopic port site implantation with ovarian transposition followed by abdominal wall irradiation and chemotherapy, which resulted in premature ovarian failure from which there was partial recovery.
Case report.
Tertiary referral university women's hospital in Sydney, Australia and private reproductive medicine clinic in California.
PATIENT(S): A 34-year-old woman who underwent laparoscopy for pelvic pain, shortly afterward followed by radical hysterectomy and pelvic lymph node dissection, who subsequently developed a laparoscopic port site recurrence, which was excised in association with ovarian transposition before abdominal wall irradiation and chemotherapy.
INTERVENTION(S): Modified IVF treatment, transabdominal oocyte retrieval, embryo cryopreservation in Australia, and transfer to a surrogate mother in the United States.
MAIN OUTCOME MEASURE(S): Pregnancy.
RESULT(S): Miscarriage in the second cycle and a twin pregnancy in the fourth cycle.
CONCLUSION(S): This is the first case report of ovarian stimulation and oocyte retrieval performed on transposed ovaries after a patient developed premature ovarian failure after radiotherapy and chemotherapy with subsequent partial ovarian recovery.
描述一例体外受精代孕妊娠病例，该患者接受了根治性子宫切除术后，又进行了腹腔镜端口部位植入物切除并卵巢移位，随后进行腹壁放疗和化疗，导致卵巢早衰，但有部分恢复。
病例报告。
澳大利亚悉尼的三级转诊大学女子医院和加利福尼亚的私立生殖医学诊所。
一名34岁女性，因盆腔疼痛接受腹腔镜检查，不久后接受了根治性子宫切除术和盆腔淋巴结清扫术，随后出现腹腔镜端口部位复发，在腹壁放疗和化疗前，与卵巢移位一起切除了复发部位。
改良体外受精治疗、经腹取卵、在澳大利亚冷冻胚胎，并将胚胎移植到美国的代孕母亲体内。
妊娠。
第二个周期流产，第四个周期双胎妊娠。
这是首例关于患者在放疗和化疗后出现卵巢早衰且随后卵巢有部分恢复的情况下，对移位卵巢进行卵巢刺激和取卵的病例报告。
