Lijffijt Marijn, Kenemans J Leon, Verbaten Marinus N, van Engeland Herman
Department of Psychopharmacology, Utrecht University, Utrecht, the Netherlands.
J Abnorm Psychol. 2005 May;114(2):216-22. doi: 10.1037/0021-843X.114.2.216.
This review discusses whether deficient inhibitory motor control is the core deficit of attention-deficit/hyperactivity disorder (ADHD). Inhibitory motor control is commonly assessed using the stop-signal paradigm. Since the last meta-analysis that was performed, 33 new studies have appeared. The current meta-analysis revealed a significant difference between ADHD patients and matched controls in stop latency (stop-signal reaction time) in both children and adults. Basic reaction time was significantly longer in children with ADHD, but not in adults, and there was a significant interaction between the elongation of the latency to stop and to respond in adults, but not in children. Deficient inhibitory motor control may be less crucial in children than in adults with ADHD.
本综述探讨了抑制性运动控制缺陷是否是注意力缺陷多动障碍(ADHD)的核心缺陷。抑制性运动控制通常使用停止信号范式进行评估。自上次进行荟萃分析以来,已出现33项新研究。当前的荟萃分析显示,ADHD患者与匹配的对照组在儿童和成人的停止潜伏期(停止信号反应时间)上存在显著差异。ADHD儿童的基本反应时间显著更长,但成人则不然,并且在成人中,停止潜伏期和反应潜伏期的延长之间存在显著交互作用,但儿童中不存在。抑制性运动控制缺陷在ADHD儿童中可能不如在成人中关键。