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巴伦西亚地区患者对美沙酮维持治疗的看法:剂量调整、参与剂量调节以及对治疗的满意度。

Patient perspectives on methadone maintenance treatment in the Valencia Region: dose adjustment, participation in dosage regulation, and satisfaction with treatment.

作者信息

Pérez de Los Cobos José, Trujols Joan, Valderrama Juan Carlos, Valero Sergi, Puig Teresa

机构信息

Addictive Behaviours Unit, Department of Psychiatry, Hospital de la Santa Creu i Sant Pau, Barcelona Autonomous University School of Medicine, Sant Antoni M(a) Claret 167, 08025 Barcelona, Spain.

出版信息

Drug Alcohol Depend. 2005 Sep 1;79(3):405-12. doi: 10.1016/j.drugalcdep.2005.03.021.

Abstract

Desired adjustment of methadone dose, perceived participation in dosage regulation, and satisfaction with methadone treatment centres were assessed in a sample of opioid-dependent patients from the Valencia Region (eastern Spain). An independent interviewer asked 278 consecutively arriving patients to answer the survey, and 165 (59.4%) completed it. Adjustment of methadone dose was assessed with a -10 to +10 visual analogue scale (VAS-MD); participation in methadone dose regulation, with specific questions; and patient satisfaction, with the Verona Service Satisfaction Scale for methadone treatment (VSSS-MT). The methadone dose (mg/d) prescribed by physicians was (mean+/-S.D.) 68.0+/-30.4. Participants scored -1.0+/-4.7 on the VAS-MD, indicating a significant downward desired adjustment of methadone dose (95% CI of -1.73 to -0.30). Of the patients surveyed, approximately one-third were, overall, content with their participation in methadone dose regulation. Overall, participants felt slightly satisfied (VSSS-MT=3.5+/-0.6) with the centres. Patients treated with a methadone dose of < 60 mg/d felt more satisfied than those treated with 60-100 mg/d. Information about dose changes was the only continuous methadone dose variable related with satisfaction that was found in a multiple regression analysis, which accounted for only 2.0% of the variance in VSSS-MT overall scores. In conclusion, patients' opinions on methadone dose and patient satisfaction are only very weakly related when methadone treatment is implemented as in the Valencia Region.

摘要

在来自西班牙东部巴伦西亚地区的阿片类药物依赖患者样本中,评估了美沙酮剂量的期望调整、在剂量调整中的感知参与度以及对美沙酮治疗中心的满意度。一名独立访谈者要求278名连续前来的患者回答调查问卷,其中165名(59.4%)完成了调查。美沙酮剂量的调整采用-10至+10的视觉模拟量表(VAS-MD)进行评估;美沙酮剂量调整的参与度通过特定问题进行评估;患者满意度则采用美沙酮治疗的维罗纳服务满意度量表(VSSS-MT)进行评估。医生开具的美沙酮剂量(mg/d)为(均值±标准差)68.0±30.4。参与者在VAS-MD上的得分为-1.0±4.7,表明美沙酮剂量存在显著的期望下调(95%置信区间为-1.73至-0.30)。在接受调查的患者中,总体而言,约三分之一的患者对自己参与美沙酮剂量调整感到满意。总体而言,参与者对这些中心感到略有满意(VSSS-MT = 3.5±0.6)。接受美沙酮剂量<60 mg/d治疗的患者比接受60-100 mg/d治疗的患者感觉更满意。在多元回归分析中发现,关于剂量变化的信息是与满意度相关的唯一连续美沙酮剂量变量,其仅占VSSS-MT总分方差的2.0%。总之,在巴伦西亚地区实施美沙酮治疗时,患者对美沙酮剂量的看法与患者满意度之间的关联非常微弱。

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