Kaykçoğlu Meral, Hasdemir Can, Eroğlu Zuhal, Kosova Buket, Can Levent H, Ildizli Muge, Yavuzgil Oguz, Payzin Serdar, Turkoglu Cuneyt
Department of Cardiology, Ege University, Medical School, 11/2 Bornova Izmir, Turkey.
Blood Coagul Fibrinolysis. 2005 Jun;16(4):281-6. doi: 10.1097/01.mbc.0000169221.38797.9c.
Although factor V Leiden mutation, is the most common established genetic risk factor for venous thrombosis, its effect on the development of myocardial infarction remains unclear. We describe a family case of homozygous factor V Leiden mutation in two siblings presenting with acute myocardial infarction as a rare cause of myocardial infarction in the young.
尽管因子V莱顿突变是静脉血栓形成最常见的确立的遗传危险因素，但其对心肌梗死发生发展的影响仍不明确。我们描述了一个家族病例，两名患有急性心肌梗死的兄弟姐妹存在纯合子因子V莱顿突变，这是年轻人心肌梗死的罕见病因。
