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早发性心肌梗死:日益严峻的威胁。

Premature Myocardial Infarction: A Rising Threat.

机构信息

Department of Cardiology, Faculty of Medicine, Ege University, Izmir, Turkey.

出版信息

Balkan Med J. 2022 Mar 14;39(2):83-95. doi: 10.4274/balkanmedj.galenos.2022-2-19.

Abstract

Myocardial infarction mostly presents with atypical signs and symptoms and has different risk factors in young individuals compared to older individuals. These risk factors are often preventable, therefore recognizing them and taking precautions can save these patients from suffering myocardial infarction. Scarcity of studies and lack of guidelines for assessment and management of young MI patients, make it more challenging for these individuals to get accurate medical care, even though MI in this age group is on the rise. Traditional risk factors, such as smoking, hyperlipidemia, hypertension, male sex, obesity, and family history of premature cardiovascular disease, contribute to the risk of myocardial infarction at a young age, but additional non-traditional risk factors, such as substance abuse, thrombophilia, coronary anomalies, immune disease, allergic reactions, and psychological stressors, uniquely contribute to the risk profile of young individuals. This review is aimed to discuss and guide the risk factor assessment for the development of myocardial infarction in young individuals based on current evidence and our >20-year of experience in Young Myocardial Infarction Clinic.

摘要

心肌梗死大多表现为非典型症状和体征,且年轻人与老年人相比,其危险因素也有所不同。这些危险因素通常是可以预防的,因此认识到这些危险因素并采取预防措施,可以使这些患者免于遭受心肌梗死的痛苦。由于缺乏针对年轻心肌梗死患者评估和管理的研究和指南,因此这些人更难以获得准确的医疗护理,尽管该年龄段的心肌梗死发病率正在上升。传统的危险因素,如吸烟、高血脂、高血压、男性、肥胖和早发性心血管疾病家族史,会增加年轻时发生心肌梗死的风险,但其他非传统的危险因素,如药物滥用、血栓形成倾向、冠状动脉异常、自身免疫性疾病、过敏反应和心理应激源,也会对年轻人的风险状况产生独特的影响。本综述旨在根据现有证据和我们在“青年心肌梗死诊所”的 20 多年经验,讨论和指导年轻人心肌梗死发展的危险因素评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3397/8941233/6f74d26533eb/BMJ-39-83-g1.jpg

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