Suppr超能文献

乳制品和母乳中的高氯酸盐与碘化物。

Perchlorate and iodide in dairy and breast milk.

作者信息

Kirk Andrea B, Martinelango P Kalyani, Tian Kang, Dutta Aniruddha, Smith Ernest E, Dasgupta Purnendu K

机构信息

The Institute of Environmental and Human Health, Texas Tech University, Lubbock, Texas 79409-1163, USA.

出版信息

Environ Sci Technol. 2005 Apr 1;39(7):2011-7. doi: 10.1021/es048118t.

Abstract

Perchlorate inhibits iodide uptake and may impair thyroid and neurodevelopment in infants. Recently, we unambiguously identified the presence of perchlorate in all seven brands of dairy milk randomly purchased from grocery stores in Lubbock, TX. How widespread is perchlorate in milk? Perchlorate in 47 dairy milk samples from 11 states and in 36 human milk samples from 18 states were measured. Iodide was also measured in a number of the samples. Perchlorate was detectable in 81 of 82 samples. The dairy and breast milk means were, respectively, 2.0 and 10.5 microg/L with the corresponding maximum values of 11 and 92 microg/L. Perchlorate is present in virtually all milk samples, the average concentration in breast milk is five times higher than in dairy milk. Although the number of available measurements are few at this point, for breast milk samples with a perchlorate content greater than 10 microg/L, the iodide content is linearly correlated with the inverse of the perchlorate concentration with a r2 of >0.9 (n = 6). The presence of perchlorate in the milk lowers the iodide content and may impair thyroid development in infants. On the basis of limited available data, iodide levels in breast milk may be significantly lower than it was two decades ago. Recommended iodine intake by pregnant and lactating women may need to be revised upward.

摘要

高氯酸盐会抑制碘的摄取,可能损害婴儿的甲状腺及神经发育。最近,我们明确鉴定出从得克萨斯州拉伯克市杂货店随机购买的所有七个品牌的牛奶中均存在高氯酸盐。高氯酸盐在牛奶中的分布有多广泛?我们测定了来自11个州的47份牛奶样本和来自18个州的36份母乳样本中的高氯酸盐含量。还对一些样本中的碘含量进行了测定。82份样本中有81份检测出高氯酸盐。牛奶和母乳中的平均含量分别为2.0和10.5微克/升,相应的最大值分别为11和92微克/升。几乎所有牛奶样本中都存在高氯酸盐,母乳中的平均浓度比牛奶中的高五倍。尽管目前可用的测量数据较少,但对于高氯酸盐含量大于10微克/升的母乳样本,碘含量与高氯酸盐浓度的倒数呈线性相关,r2>0.9(n = 6)。牛奶中高氯酸盐的存在会降低碘含量,并可能损害婴儿的甲状腺发育。基于有限的现有数据,母乳中的碘含量可能比二十年前显著降低。孕妇和哺乳期妇女的碘摄入量建议可能需要向上调整。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验