Whittaker David R, Dwyer Jeff, Fillinger Mark F
Section of Vascular Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA.
J Vasc Surg. 2005 Apr;41(4):575-83. doi: 10.1016/j.jvs.2005.01.033.
During endovascular abdominal aortic aneurysm (AAA) repair (EVAR), the rapid deployment of the Gore Excluder endograft may be associated with anatomic shortening of the endograft path. This shortened path may result in coverage of the hypogastric artery origin or overly conservative graft length selection that may lead to unnecessary extensions. We quantified the degree of path alteration with this endograft and developed an algorithm to predict it.
Preoperative and postoperative three-dimensional (3D) computed tomographic (CT) scans were evaluated for 50 consecutive patients with Gore Excluder endografts by using 21 anatomic measurements and 6 calculated indices. Measurements were evaluated as if only 3D lumen centerline measurements were available, rather than complete 3D computer-aided measurement and "virtual graft" simulation. Tortuosity was quantitated from the renal artery to the hypogastric origin, using the difference between a straight line and the lumen centerline.
The endograft was deployed successfully in all cases. The graft end points were typically quite close to the preoperative plan: mean renal artery-to-graft distance was within 2.0 +/- .5 mm, and the limb end point-to-hypogastric origin differed by an average of only 1.8 +/- 1.6 mm. Although accurate in most cases, the actual graft path shortened 1 cm or more relative to the centerline in 11% of limbs. On univariate analysis, determinants of alteration of >1 cm in the graft deployment path were (1) aortoiliac tortuosity (renal-to-hypogastric artery, P < .002), (2) the degree of planned graft rotation (73% of cases altered >10 mm were in the rotated position, P < .05), and (3) the insertion side (73% of alterations >or=10 mm were ipsilateral to the main device, P < .05). On multivariate analysis, the renal-to-hypogastric artery tortuosity index (RHTI) was significant ( P < .004), and device type and rotation approached significance ( P < .08). We developed a classification scheme based on RHTI to predict the risk of alteration of the graft path >or=1 cm (low risk, 0%; medium risk, 10%; high risk, 25%) and an algorithm to predict the degree of alteration of the anatomy that reduced the number of cases shortening >or=1 cm to zero.
The graft deployment path will be altered significantly in a minority of cases with the Gore Excluder endograft, but this can cause hypogastric occlusion or other problems. Anatomic shortening is predictable from morphologic features such as tortuosity, graft insertion side, and rotation. We developed an algorithm based on a tortuosity index that quantitates the risk and degree of shortening associated with endograft deployment.
在血管腔内腹主动脉瘤(AAA)修复术(EVAR)中,戈尔封堵型血管内移植物的快速展开可能与移植物路径的解剖学缩短有关。这种缩短的路径可能导致对下腹动脉起始部的覆盖,或者导致移植物长度选择过于保守,进而可能导致不必要的延长。我们对使用这种移植物时路径改变的程度进行了量化,并开发了一种算法来预测它。
对连续50例使用戈尔封堵型血管内移植物的患者进行术前和术后三维(3D)计算机断层扫描(CT)评估,采用21项解剖学测量指标和6项计算指数。这些测量是在假设只有3D管腔中心线测量可用的情况下进行评估的,而不是完整的3D计算机辅助测量和“虚拟移植物”模拟。从肾动脉到下腹动脉起始部的迂曲度通过直线与管腔中心线之间的差异进行量化。
所有病例中移植物均成功展开。移植物端点通常与术前计划非常接近:肾动脉到移植物的平均距离在2.0±0.5mm以内,肢体端点到下腹动脉起始部的平均差异仅为1.8±1.6mm。尽管在大多数情况下是准确的,但在11%的肢体中,实际移植物路径相对于中心线缩短了1cm或更多。单因素分析显示,移植物展开路径改变>1cm的决定因素为:(1)主-髂动脉迂曲度(肾动脉到下腹动脉,P<0.002);(2)计划的移植物旋转程度(73%改变>10mm的病例处于旋转位置,P<0.05);(3)插入侧(73%改变≥10mm的情况与主装置同侧,P<0.05)。多因素分析显示,肾动脉到下腹动脉迂曲度指数(RHTI)具有显著性(P<0.004),移植物类型和旋转接近显著性(P<0.08)。我们基于RHTI制定了一种分类方案,以预测移植物路径改变≥1cm的风险(低风险,0%;中风险,10%;高风险,25%),并开发了一种算法来预测解剖结构改变的程度,该算法将缩短≥1cm的病例数减少至零。
少数使用戈尔封堵型血管内移植物的病例中,移植物展开路径会发生显著改变,但这可能导致下腹动脉闭塞或其他问题。解剖学缩短可通过迂曲度、移植物插入侧和旋转等形态学特征进行预测。我们基于迂曲度指数开发了一种算法,该算法可量化与移植物展开相关的缩短风险和程度。