Siemens D Robert, Schulze Karleen M, Mackillop William J, Brundage Michael D, Groome Patti A
Department of Urology, Queen's University, Kingston, Ontario, Canada.
Can J Urol. 2005 Apr;12(2):2568-74.
Despite the high incidence of prostate cancer in Canada, there is currently limited information describing how these patients are being managed. The aim of this study was to review the surgical waiting times for radical prostatectomy in Ontario, utilizing existing population-based cancer databases, and to describe factors associated with prolonged waiting times.
This is a retrospective, population-based, observational study of men diagnosed with prostate cancer in Ontario between 1980 and 2000. The sources of data include the Ontario Cancer Registry linked to hospital discharge data, as well as census data from Statistics Canada. Study variables include age, county of residence, teaching hospital status, hospital surgical volume, area-level median household income and cause-specific survival. Waiting times were compared across study variables using univariate and graphical methods. Survival was compared across geographic regions with differing average wait times.
We identified 9524 men treated with radical prostatectomy in Ontario over the study period and found the percentage of all patients with the disease who were treated surgically increasing from 3% to 20% over the last 2 decades. The overall time to prostatectomy has almost doubled with a median waiting time of 55 days in earlier eras to 91 days in 1996-2000. A few counties had significantly different wait times, whereas age and socio-economic factors were not associated with wait times across most eras. In the most recent eras, acute care hospitals and hospitals with higher surgical volumes had significantly higher waiting times (up to 20 days longer in 1996-2000, p<0.0001). Patients living in regions with the shortest wait times had statistically significant worse survival (p=0.02), implying that triaging has a greater impact than the potential effect of prolonged waits.
The observed increases in waiting times for radical prostatectomy from this study are similar to the known increases in waiting times for radiotherapy. This increased time to treatment is an illustration of the stress on the health care system in Ontario.
尽管加拿大前列腺癌发病率很高,但目前关于这些患者的治疗管理情况的信息有限。本研究的目的是利用现有的基于人群的癌症数据库,回顾安大略省根治性前列腺切除术的手术等待时间,并描述与等待时间延长相关的因素。
这是一项基于人群的回顾性观察研究,研究对象为1980年至2000年间在安大略省被诊断为前列腺癌的男性。数据来源包括与医院出院数据相关联的安大略癌症登记处,以及加拿大统计局的人口普查数据。研究变量包括年龄、居住县、教学医院状况、医院手术量、地区层面的家庭收入中位数以及特定病因生存率。使用单变量和图形方法对各研究变量的等待时间进行比较。对平均等待时间不同的地理区域的生存率进行比较。
在研究期间,我们确定了安大略省9524例接受根治性前列腺切除术的男性患者,并发现过去20年中接受手术治疗的所有前列腺癌患者的比例从3%增至20%。前列腺切除术的总体等待时间几乎翻了一番,早期的中位等待时间为55天,而在1996 - 2000年为91天。少数几个县的等待时间存在显著差异,而在大多数时期,年龄和社会经济因素与等待时间无关。在最近时期,急症医院和手术量较高的医院等待时间显著更长(1996 - 2000年长达20天,p<0.0001)。居住在等待时间最短地区的患者生存率在统计学上显著较差(p = 0.02),这意味着分诊的影响大于等待时间延长的潜在影响。
本研究中观察到的根治性前列腺切除术等待时间的增加与已知的放射治疗等待时间的增加相似。治疗时间的增加说明了安大略省医疗保健系统所面临的压力。