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尸检采集标本在暴发性脑膜炎球菌败血症诊断中的意义

Interest of postmortem-collected specimens in the diagnosis of fulminant meningococcal sepsis.

作者信息

Ploy Marie-Cécile, Garnier Fabien, Languepin Jeanne, Fermeaux Véronique, Martin Christian, Denis François

机构信息

Laboratoire de Bactériologie-Virologie-Hygiène, CHU Dupuytren, 87042 Limoges Cedex, France.

出版信息

Diagn Microbiol Infect Dis. 2005 May;52(1):65-6. doi: 10.1016/j.diagmicrobio.2004.12.012.

DOI:10.1016/j.diagmicrobio.2004.12.012
PMID:15878445
Abstract

We reported the case of a child who died of purpura fulminans. The diagnosis of Neisseria meningitidis serogroup C could be assessed using postmortem specimens collected up to 10 h after death. We were able to identify the bacteria by culture and/or PCR on samples without having autopsy performed. Soluble antigens were also detected in serum.

摘要

我们报告了一例死于暴发性紫癜的儿童病例。利用死后长达10小时采集的尸检标本,可评估C群脑膜炎奈瑟菌的诊断。我们能够在未进行尸检的情况下,通过对样本进行培养和/或聚合酶链反应(PCR)来鉴定细菌。血清中也检测到了可溶性抗原。

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Interest of postmortem-collected specimens in the diagnosis of fulminant meningococcal sepsis.尸检采集标本在暴发性脑膜炎球菌败血症诊断中的意义
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引用本文的文献

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Post-Mortem Investigations for the Diagnosis of Sepsis: A Review of Literature.用于脓毒症诊断的尸检调查:文献综述
Diagnostics (Basel). 2020 Oct 20;10(10):849. doi: 10.3390/diagnostics10100849.
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Fatal meningococcal meningitis in a 2-year-old child: A case report.
World J Clin Cases. 2019 Mar 6;7(5):636-641. doi: 10.12998/wjcc.v7.i5.636.
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Neisseria meningitides Can Survive in Corpses for At Least Eleven Days.脑膜炎奈瑟菌可在尸体中存活至少11天。
Front Cell Infect Microbiol. 2016 Jul 13;6:74. doi: 10.3389/fcimb.2016.00074. eCollection 2016.
4
Detection of Neisseria meningitidis DNA from skin lesion biopsy using real-time PCR: usefulness in the aetiological diagnosis of purpura fulminans.使用实时聚合酶链反应从皮肤病变活检中检测脑膜炎奈瑟菌DNA:在暴发性紫癜病因诊断中的作用
Intensive Care Med. 2007 Jul;33(7):1168-1172. doi: 10.1007/s00134-007-0667-2. Epub 2007 May 15.