Head C E G, Thorne S A
Department of Cardiology, University Hospital, Birmingham, UK.
Postgrad Med J. 2005 May;81(955):292-8. doi: 10.1136/pgmj.2004.026625.
Congenital heart disease is now more prevalent than acquired in pregnancy in the developed world. In pregnancy the fall in systemic vascular resistance and increase in blood volume and cardiac output can cause functional deterioration in certain conditions. A minimally symptomatic woman with good ventricular function, normal oxygen saturation, and no left heart obstruction should tolerate pregnancy well. Women with pulmonary hypertension or dilated aortic root (pre-replacement) should be counselled against pregnancy and given appropriate contraceptive advice. The optimum management of a pregnant woman with a metallic prosthetic valve remains to be determined.
在发达国家,先天性心脏病如今在孕期比后天性心脏病更为常见。在孕期,全身血管阻力下降、血容量和心输出量增加,在某些情况下会导致功能恶化。心室功能良好、氧饱和度正常且无左心梗阻的症状轻微的女性通常能很好地耐受妊娠。患有肺动脉高压或扩张性主动脉根部(置换前)的女性应被建议避免妊娠并给予适当的避孕建议。金属人工瓣膜置换术后孕妇的最佳管理方案仍有待确定。