Zluvova Jitka, Janousek Bohuslav, Negrutiu Ioan, Vyskot Boris
Laboratory of Plant Developmental Genetics, Institute of Biophysics, Academy of Sciences of the Czech Republic, 612 65 Brno, Czech Republic.
Genetics. 2005 Jul;170(3):1431-4. doi: 10.1534/genetics.105.040444. Epub 2005 May 6.
Here we compare gene orders on the Silene latifolia sex chromosomes. On the basis of the deletion mapping results (11 markers and 23 independent Y chromosome deletion lines used), we conclude that a part of the Y chromosome (covering a region corresponding to at least 23.9 cM on the X chromosome) has been inverted. The gradient in silent-site divergence suggests that this inversion took place after the recombination arrest in this region. Because recombination arrest events followed by Y chromosome rearrangements also have been found in the human Y chromosome, this process seems to be a general evolutionary pathway.
在此,我们比较了宽叶蝇子草性染色体上的基因顺序。基于缺失定位结果(使用了11个标记和23个独立的Y染色体缺失系),我们得出结论,Y染色体的一部分(覆盖了对应于X染色体上至少23.9 cM的区域)发生了倒位。沉默位点分歧的梯度表明,这种倒位发生在该区域的重组停滞之后。由于在人类Y染色体中也发现了重组停滞事件之后接着发生Y染色体重排的情况,所以这个过程似乎是一种普遍的进化途径。