Schrager Sarina
Department of Family Medicine, University of Wisconsin-Madison, Madison, WI 53715, USA.
J Am Board Fam Pract. 2005 May-Jun;18(3):205-10. doi: 10.3122/jabfm.18.3.205.
Obesity is increasing in the United States in epidemic proportions. Epidemiologic data suggest that people with high calcium intake have a lower prevalence of overweight, obesity, and insulin resistance syndrome. Studies in transgenic mice have demonstrated that calcium influences adipocyte metabolism. High calcium intake depresses levels of parathyroid hormone and 1,25-hydroxy vitamin D. These decreased hormone levels cause decreases in intracellular calcium, thereby inhibiting lipogenesis and stimulating lipolysis. High dietary calcium intakes also increases excretion of fecal fat and may increase core body temperature. Calcium from dairy products seems to have more of an impact than calcium from dietary supplements. Primary care providers should include recommendations about adequate calcium intake in standard dietary counseling about weight management.
在美国，肥胖现象正以流行的比例不断增加。流行病学数据表明，钙摄入量高的人群超重、肥胖及胰岛素抵抗综合征的患病率较低。对转基因小鼠的研究表明，钙会影响脂肪细胞代谢。高钙摄入量会降低甲状旁腺激素和1,25 - 二羟维生素D的水平。这些激素水平的降低会导致细胞内钙含量减少，从而抑制脂肪生成并刺激脂肪分解。高膳食钙摄入量还会增加粪便脂肪的排泄，并且可能会提高核心体温。来自乳制品的钙似乎比膳食补充剂中的钙影响更大。初级保健提供者应在关于体重管理的标准饮食咨询中纳入有关充足钙摄入量的建议。
