Zaks Karen L, Tan Emmeline O, Thrall Mary Anna
Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO 80524, USA.
J Am Vet Med Assoc. 2005 May 1;226(9):1516-8, 1500. doi: 10.2460/javma.2005.226.1516.
A 5-year-old pit bull-type dog was examined because of lethargy and black feces, and a presumptive diagnosis of methemoglobinemia was made on the basis of grossly visible brown discoloration of the mucous membranes and urine. Heinz body formation was seen on examination of blood smears, and severe anemia developed 3 days later. The dog did not have any history of exposure to toxins or drugs that have been associated with Heinz body formation. The only remarkable historical finding was that the dog had been wandering loose the day prior to initial examination and returned home smelling strongly of skunk spray. Skunk spray contains thiols and other compounds that are strong oxidizing agents. It was speculated that the methemoglobinemia and Heinz body anemia were a result of exposure to these compounds. Skunk interactions with dogs usually have malodorous but otherwise harmless results. However, findings in this dog suggest that more serious consequences may develop in isolated cases.
一只5岁的比特斗牛梗犬因嗜睡和黑色粪便接受检查，基于肉眼可见的黏膜和尿液褐色变色，初步诊断为高铁血红蛋白血症。血液涂片检查发现有海因茨小体形成，3天后出现严重贫血。这只狗没有任何接触与海因茨小体形成相关毒素或药物的病史。唯一值得注意的既往史是，这只狗在初次检查前一天走失，回家时身上有浓烈的臭鼬喷雾气味。臭鼬喷雾含有硫醇和其他强氧化剂化合物。据推测，高铁血红蛋白血症和海因茨小体贫血是接触这些化合物所致。臭鼬与狗的接触通常会产生恶臭但无其他危害的结果。然而，这只狗的情况表明，个别病例可能会出现更严重的后果。
