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柔脑膜转移患者的脑室腹腔分流术

Ventriculoperitoneal shunt in patients with leptomeningeal metastasis.

作者信息

Omuro Antonio M P, Lallana Enrico C, Bilsky Mark H, DeAngelis Lisa M

机构信息

Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

出版信息

Neurology. 2005 May 10;64(9):1625-7. doi: 10.1212/01.WNL.0000160396.69050.DC.

Abstract

The authors reviewed 37 patients with leptomeningeal metastasis (LM) who required a ventriculoperitoneal shunt (VP shunt) for management of intracranial hypertension. Improvement was seen in 27 (77%) patients; subdural hematoma developed in one and shunt malfunction in three. Median overall survival was 2 months (range 2 days to 3.6 years) after VP shunt placement, but there was no procedure-related mortality. The prognosis of LM remained poor, but VP shunt can be an effective palliative tool when required.

摘要

作者回顾了37例需要行脑室腹腔分流术(VP分流术)来治疗颅内高压的柔脑膜转移(LM)患者。27例(77%)患者病情得到改善;1例发生硬膜下血肿,3例出现分流器故障。VP分流术后的中位总生存期为2个月(范围为2天至3.6年),但无手术相关死亡。LM的预后仍然很差,但在必要时VP分流术可以是一种有效的姑息治疗手段。

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