Guyon G, Foulongne V, Vande Perre P, Rodière M
Service de pédiatrie infectieuse, hôpital Arnaud-de-Villeneuve, 371, avenue du Doyen-Gaston-Giraud, 34295 Montpellier cedex, France.
Arch Pediatr. 2005 Apr;12 Suppl 1:S61-3. doi: 10.1016/s0929-693x(05)80015-6.
Human metapneumovirus (hmpv) is a newly identified agent responsible for respiratory tract infections in children, especially before one year of age. A prospective epidemiological study is underway to better define the spectrum of the disease in France.
From November 2003 to November 2004, rhinopharyngeal aspirates were obtained from all children under five years of age admitted to the hospital with upper or lower airway symptoms. Viral identification was made using gene amplification.
Among 355 evaluable samples to date, 34 were positive for hmpv genome. Mean age of infected children was 6.4 months, 20.5% were prematurely born infants. The prognosis is usually good.
Our preliminary results are consistent with the available literature data. Further studies are needed to better define the exact frequency and morbidity of this newly recognized infection, both in hospital and community settings.
人偏肺病毒（hmpv）是一种新发现的可导致儿童呼吸道感染的病原体，尤其是一岁以下儿童。法国正在进行一项前瞻性流行病学研究，以更好地界定该疾病的范围。
2003年11月至2004年11月，从所有因上呼吸道或下呼吸道症状入院的五岁以下儿童中获取鼻咽抽吸物。通过基因扩增进行病毒鉴定。
在迄今355份可评估样本中，34份hmpv基因组呈阳性。受感染儿童的平均年龄为6.4个月，20.5%为早产儿。预后通常良好。
我们的初步结果与现有文献数据一致。需要进一步研究，以更好地界定这种新发现感染在医院和社区环境中的准确发病率和发病情况。
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