Stein Michael, Herman Debra S, Trisvan Elizabeth, Pirraglia Paul, Engler Patricia, Anderson Bradley J
Rhode Island Hospital, Division of General Internal Medicine, Providence, Rhode Island 02903, USA.
Alcohol Clin Exp Res. 2005 May;29(5):837-43. doi: 10.1097/01.alc.0000164363.40533.e0.
This study was undertaken to determine if alcohol use is associated with sexual risk taking among human immunodeficiency virus (HIV)-infected persons.
Cross-sectional interviews of 262 HIV-infected patients in the Brown University AIDS Program were performed. Factors associated with any sexual activity, unsafe sexual activity, and a 4-fold typology of sexual risk were examined. Alcohol measures included drinking days, drinks per drinking day, binge drinking, and hazardous alcohol use.
The sample was 58% male and 40% white; 67% of patients were self-identified as heterosexual, and 48% drank alcohol. Nearly two thirds of patients reported sexual activity in the past 6 months, with 38% reporting unprotected sex during that period. All measures of alcohol use were significantly associated with any sexual activity and with unsafe sexual behavior. As an example, controlling for age, HIV transmission risk, marital status, and HIV clinical indicators, hazardous drinkers were 5.64 times more likely to report unprotected sex and have multiple partners (p < 0.01) than were those not drinking at hazardous levels.
A high proportion of HIV-infected persons were sexually active and having unsafe sex. Alcohol, at all levels of use, was associated with increased sexual risk taking.
本研究旨在确定饮酒是否与人类免疫缺陷病毒（HIV）感染者的性风险行为相关。
对布朗大学艾滋病项目中的262名HIV感染者进行了横断面访谈。研究了与任何性行为、不安全性行为以及性风险的四重分类相关的因素。酒精使用的衡量指标包括饮酒天数、每日饮酒量、暴饮以及有害饮酒。
样本中58%为男性，40%为白人；67%的患者自认为是异性恋，48%饮酒。近三分之二的患者报告在过去6个月中有性行为，其中38%报告在此期间有未采取保护措施的性行为。所有酒精使用指标均与任何性行为以及不安全性行为显著相关。例如，在控制年龄、HIV传播风险、婚姻状况和HIV临床指标后，有害饮酒者报告未采取保护措施的性行为并拥有多个性伴侣的可能性比未处于有害饮酒水平的人高5.64倍（p < 0.01）。
很大比例的HIV感染者有性活动且存在不安全的性行为。在所有饮酒水平下，酒精都与性风险行为增加相关。
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