Chen Yung-Chang, Cadnapaphornchai Melissa A, Schrier Robert W
Department of Medicine, University of Colorado Health Sciences Center, Denver, CO 80262, USA.
Biol Cell. 2005 Jun;97(6):357-71. doi: 10.1042/BC20040041.
Following the discovery of the aquaporin-1 water channel over a decade ago, molecular techniques have been developed to examine the role of renal aquaporin water channels under numerous physiological and pathological conditions. The present article reviews current knowledge regarding the function and dysfunction of renal aquaporins in disorders of water metabolism.
十多年前发现水通道蛋白-1水通道后,已开发出分子技术来研究肾脏水通道蛋白在多种生理和病理条件下的作用。本文综述了关于肾脏水通道蛋白在水代谢紊乱中的功能和功能障碍的现有知识。