Kusleikaite Neda, Bumblyte Inga Arūne, Razukeviciene Loreta, Sedlickaite Diana, Rinkūnas Kornelijus
Clinic of Nephrology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania.
Medicina (Kaunas). 2005;41 Suppl 1:69-74.
The objective of this study was to determine the rate of sleep disorders in patients on hemodialysis and to evaluate the association between quality of sleep and quality of life in these patients.
A total of 81 hemodialysis patients were enrolled in the study. Quality of sleep was assessed using the Pittsburgh Sleep Quality Index (PSQI): higher scores indicate worse sleep quality. Health-related quality of life was evaluated using the Medical Outcomes Study 36-item Short Form (SF-36) questionnaire.
In the present study 54 dialysis patients (66.7%) were "poor sleepers" (PSQI>5). The SF-36 mental component summary (PCS) and physical component summary (MCS) correlated with the global PSQI score (PCS, r=-0.463, p<0.001; MCS, r=-0.426, p<0.001), age (PCS, r=-0.330, p=0.003; MCS, r=-0.381, p<0.001), hemoglobin (PCS, r=0.289, p=0.009; MCS, r=0.301, p=0.006), comorbidity (PCS, r=-0.286, p=0.01; MCS, r=-0.283, p=0.011). Dialysis patients with global PSQI< or =5 ("good sleepers") had higher SF-36 PCS and MCS scores (PCS, 51.15+/-17.2 vs. 34.72+/-16.58, p<0.001; MCS, 59.52+/-17.43 vs. 41.92+/-18.34, p<0.001) and higher hemoglobin levels (102.74+/-12.34 g/l vs. 95.67+/-10.57 g/l, p=0.009) compared with "poor sleepers" (PSQI>5).
In the present study two-thirds of dialysis patients (66.7%) were "poor sleepers". Lower hemoglobin levels correlated with worse quality of sleep and quality of life. We hypothesize that correction of anemia may improve quality of life in patients on hemodialysis. Poor sleep is associated with lower quality of life in hemodialysis patients.
本研究的目的是确定血液透析患者睡眠障碍的发生率，并评估这些患者的睡眠质量与生活质量之间的关联。
共有81名血液透析患者纳入本研究。使用匹兹堡睡眠质量指数（PSQI）评估睡眠质量：分数越高表明睡眠质量越差。使用医学结局研究36项简短问卷（SF-36）评估与健康相关的生活质量。
在本研究中，54名透析患者（66.7%）为“睡眠不佳者”（PSQI>5）。SF-36精神健康综合评分（PCS）和生理健康综合评分（MCS）与PSQI总评分相关（PCS，r=-0.463，p<0.001；MCS，r=-0.426，p<0.001）、年龄（PCS，r=-0.330，p=0.003；MCS，r=-0.381，p<0.001）、血红蛋白（PCS，r=0.289，p=0.009；MCS，r=0.301，p=0.006）、合并症（PCS，r=-0.286，p=0.01；MCS，r=-0.283，p=0.011）。PSQI总评分≤5的透析患者（“睡眠良好者”）的SF-36 PCS和MCS评分更高（PCS，51.15±17.2 vs. 34.72±16.58，p<0.001；MCS，59.52±17.43 vs. 41.92±18.34，p<0.001），且血红蛋白水平更高（102.74±12.34 g/l vs. 95.67±10.57 g/l，p=0.009），与“睡眠不佳者”（PSQI>5）相比。
在本研究中，三分之二的透析患者（66.7%）为“睡眠不佳者”。较低的血红蛋白水平与较差的睡眠质量和生活质量相关。我们推测纠正贫血可能改善血液透析患者的生活质量。睡眠不佳与血液透析患者较低的生活质量相关。
