辣椒素治疗外阴前庭炎
Capsaicin for the treatment of vulvar vestibulitis.
作者信息
Steinberg Adam C, Oyama Ian A, Rejba Amy E, Kellogg-Spadt Susan, Whitmore Kristene E
机构信息
University of Medicine and Dentistry of New Jersey/Robert Wood Johnson Medical School-Camden, Cooper University Hospital, USA.
出版信息
Am J Obstet Gynecol. 2005 May;192(5):1549-53. doi: 10.1016/j.ajog.2004.10.626.
OBJECTIVE
The purpose of this study was to evaluate the use of local capsaicin cream as an effective treatment for patients with documented vulvar vestibulitis syndrome.
STUDY DESIGN
A retrospective chart review was performed for patients who received a diagnosis of vulvar vestibulitis syndrome that was treated with capsaicin. Patients performed local application of capsaicin 0.025% cream for 20 minutes daily for 12 weeks. A comparison was made between the pre- and posttreatment Kaufman touch test to evaluate discomfort. The Marinoff dyspareunia scale was also used to assess pre- and posttreatment.
RESULTS
The sum of the Kaufman touch test scores before the treatment (13.2 +/- 4.9) compared with the scores after treatment (4.8 +/- 3.8) was statistically improved (P < .001). A significant improvement was also observed at each individual site (P < .001). The Marinoff dyspareunia scale also showed a significant improvement (P < .001).
CONCLUSION
Vulvar vestibulitis syndrome that is treated with capsaicin significantly decreases discomfort and allows for more frequent sexual relations.
目的
本研究的目的是评估局部使用辣椒素乳膏对已确诊的外阴前庭炎综合征患者的治疗效果。
研究设计
对诊断为外阴前庭炎综合征并接受辣椒素治疗的患者进行回顾性病历审查。患者每天局部涂抹0.025%辣椒素乳膏20分钟，持续12周。通过比较治疗前后的考夫曼触觉试验来评估不适程度。还使用马里诺夫性交困难量表评估治疗前后情况。
结果
治疗前考夫曼触觉试验得分总和为（13.2±4.9），治疗后为（4.8±3.8），差异有统计学意义（P<.001）。各个部位也均有显著改善（P<.001）。马里诺夫性交困难量表也显示有显著改善（P<.001）。
结论
用辣椒素治疗外阴前庭炎综合征可显著减轻不适，并使性交频率增加。
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