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[德国重症监护病房的死亡率:死于医院感染还是伴有医院感染?]

[Mortality in German intensive care units: dying from or with a nosocomial infection?].

作者信息

Gastmeier P, Sohr D, Geffers C, Zuschneid I, Behnke M, Rüden H

机构信息

Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover.

出版信息

Anasthesiol Intensivmed Notfallmed Schmerzther. 2005 May;40(5):267-72. doi: 10.1055/s-2005-861354.

Abstract

OBJECTIVE

To describe mortality from intensive care unit acquired infections in German ICUs.

METHODS

The hospital infection surveillance system (KISS = Krankenhaus-Infektions-Surveillance-System) started in Germany in January 1997 as a nationwide surveillance project for the voluntary registration of nosocomial infections. For ICUs reporting focuses on pneumonia and primary bloodstream infections. The data collected for each patient who acquires a nosocomial infection include outcome information. Data of a recent French study and the Statistical Yearbook were used to estimate the annual number of ICU acquired infections contributing to death in Germany.

RESULTS

Data from 897 774 ICU patients were considered for the analysis (January 1997-June 2004). ICU mortality of patients with nosocomial pneumonia was 8.8 %, of patients with primary bloodstream infection was 10,9 %. Of the ICU patients with nosocomial pneumonia and primary bloodstream infections about 3554 die annually, in about 1131 cases the nosocomial infection was the cause of death. It may be estimated that the ICU acquired cases of pneumonia and primary bloodstream infection contributed to the death of about 2400 patients annually in Germany.

CONCLUSION

Because of the substantial mortality of patients with ICU acquired infections preventive measures have a high priority. Further studies leading to improved infection control measures are very wellcome.

摘要

目的

描述德国重症监护病房(ICU)获得性感染导致的死亡率。

方法

医院感染监测系统(KISS = Krankenhaus-Infektions-Surveillance-System)于1997年1月在德国启动,作为一项全国性监测项目,用于自愿登记医院感染。对于ICU,报告重点关注肺炎和原发性血流感染。收集的每例发生医院感染患者的数据包括结局信息。利用法国最近一项研究的数据和《统计年鉴》来估计德国每年因ICU获得性感染导致死亡的病例数。

结果

分析纳入了897774例ICU患者的数据(1997年1月至2004年6月)。医院获得性肺炎患者的ICU死亡率为8.8%,原发性血流感染患者的ICU死亡率为10.9%。在患有医院获得性肺炎和原发性血流感染的ICU患者中,每年约有3554例死亡,其中约1131例死亡的原因是医院感染。据估计,德国每年约有2400例患者的死亡归因于ICU获得性肺炎和原发性血流感染病例。

结论

由于ICU获得性感染患者的死亡率很高,预防措施具有高度优先性。非常欢迎开展进一步研究以改进感染控制措施。

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