急性心包疾病与恶性肿瘤的关系。

Relation of acute pericardial disease to malignancy.

作者信息

Imazio Massimo, Demichelis Brunella, Parrini Iris, Favro Elisa, Beqaraj Federico, Cecchi Enrico, Pomari Franco, Demarie Daniela, Ghisio Aldo, Belli Riccardo, Bobbio Marco, Trinchero Rita

机构信息

Cardiology Department, Maria Vittoria Hospital, Torino, Italy.

出版信息

Am J Cardiol. 2005 Jun 1;95(11):1393-4. doi: 10.1016/j.amjcard.2005.01.094.

DOI:10.1016/j.amjcard.2005.01.094

PMID:15904655

Abstract

Neoplastic etiology was found in 33 of 450 patients with acute pericardial disease (7.3%). Acute pericardial disease was the first manifestation of previously unknown malignancies in 18 of 450 patients (4.0%), and lung cancer was the most common malignancy (72.2%, p = 0.02). The following clinical characteristics were associated with a greater probability of a neoplastic etiology: a history of malignancy (odds ratio [OR] 19.8), cardiac tamponade at presentation (OR 7.0), a lack of response to nonsteroidal anti-inflammatory drugs, and recurrent or incessant pericarditis (OR 10.0). A similar prognosis was found in patients with or without a history of known cancer.

摘要

450例急性心包疾病患者中，33例（7.3%）病因是肿瘤。450例患者中有18例（4.0%）急性心包疾病是先前未知恶性肿瘤的首发表现，其中肺癌最为常见（72.2%，p = 0.02）。以下临床特征与肿瘤病因的可能性较大相关：恶性肿瘤病史（比值比[OR] 19.8）、就诊时心脏压塞（OR 7.0）、对非甾体抗炎药无反应以及复发性或持续性心包炎（OR 10.0）。有或无已知癌症病史的患者预后相似。