Lee Bor-Shiunn, Chang Chun-Wei, Chen Weng-Pin, Lan Wan-Hong, Lin Chun-Pin
Graduate Institute of Clinical Dentistry, College of Medicine, National Taiwan University Hospital, No. 1, Chang-Te Street, Taipei, Taiwan, ROC.
Dent Mater. 2005 Jun;21(6):511-9. doi: 10.1016/j.dental.2004.08.002. Epub 2004 Dec 15.
An ideal material has yet to be discovered that can completely treat dentin hypersensitivity. However, if a highly biocompatible material such as bioglass, could be melted by laser irradiation to achieve better sealing depth for dentinal tubules, it may subsequently bond to dentin structures under a physiological environment and offer a prolonged therapeutic effect.
The authors used four types of energy parameters to melt the composition-modified bioglass. These four types were 30 Hz, 330 mJ/pulse (G+ mode), 30 Hz, 160 mJ/pulse (G- mode), 10 Hz, 400 mJ/pulse (D+ mode), and 10 Hz, 200 mJ/pulse (D- mode). The temperature elevation, occlusive depth of bioglass, and phase changes in the bioglass after laser irradiation were evaluated by means of scanning electron microscope (SEM), thermometer, and X-ray diffractometer (XRD).
The occlusive depths of 2 and 10 microm in the dentinal tubules were achieved when the bioglass underwent 30 Hz, 160 mJ/pulse (G- mode) and 30 Hz, 330 mJ/pulse (G+ mode) of laser treatments, respectively. The bioglass experienced a temperature increase of less than 600 degrees C, and no phase transformation was observed after Nd:YAP laser irradiation.
The melting point of a composition-modified bioglass could be reduced and its use plus Nd:YAP laser have the potential in clinical use to treat dentin hypersensitivity.
尚未发现一种能完全治疗牙本质过敏症的理想材料。然而，如果一种具有高度生物相容性的材料（如生物玻璃）能够通过激光照射熔化，以实现对牙本质小管更好的封闭深度，那么它随后可能在生理环境下与牙本质结构结合，并提供长期的治疗效果。
作者使用四种能量参数来熔化成分改性的生物玻璃。这四种参数分别是30Hz、330mJ/脉冲（G+模式），30Hz、160mJ/脉冲（G-模式），10Hz、400mJ/脉冲（D+模式）和10Hz、200mJ/脉冲（D-模式）。通过扫描电子显微镜（SEM）、温度计和X射线衍射仪（XRD）评估激光照射后生物玻璃的温度升高、封闭深度和相变。
当生物玻璃分别接受30Hz、160mJ/脉冲（G-模式）和30Hz、330mJ/脉冲（G+模式）的激光处理时，牙本质小管中的封闭深度分别达到2微米和10微米。生物玻璃的温度升高小于600摄氏度，钕：钇铝石榴石激光照射后未观察到相变。
成分改性生物玻璃的熔点可以降低，其与钕：钇铝石榴石激光联合使用在临床上有治疗牙本质过敏症的潜力。
