Bokström K, Balldin J
Department of Psychiatry and Neurochemistry, University of Göteborg, St. Jörgen's Hospital, Hisings Backa, Sweden.
Alcohol Clin Exp Res. 1992 Apr;16(2):241-9. doi: 10.1111/j.1530-0277.1992.tb01370.x.
For patients in alcohol withdrawal, there are several scales designed to assess physiological disturbances, but there seems to be a lack of scales for assessment of psychopathology. To develop and evaluate a rating scale for psychopathology, items from the Comprehensive Psychopathological Rating Scale (CPRS) were selected, and patients meeting the DSMR-III-R criteria for alcohol dependence (303.90) were rated on these items. The patients were divided into two groups according to the length of time passed since their last period of alcohol consumption. The groups are referred to as the group (n = 53) in early withdrawal, rated daily during 1 week and the group (n = 13) in late withdrawal, rated once a week for 7 weeks. To justify inclusion in the new scale, items had to either indicate psychopathology in at least half of the patients in one of the groups in withdrawal, or be sensitive to changes over time at a 0.1% level of significance. Seventeen items fulfilled one of these criteria. The scale was tested for inter-rater reliability in a new sample of patients (n = 30) in early withdrawal. Inter-rater reliability, as well as internal consistency, was found satisfactory. This new scale, capable of identifying psychopathology and changes over time, may be used alone or together with physiological scales to identify subgroups of patients undergoing withdrawal.
对于处于酒精戒断期的患者,有几种用于评估生理紊乱的量表,但似乎缺乏用于评估精神病理学的量表。为了开发和评估一种精神病理评定量表,从综合精神病理评定量表(CPRS)中选取项目,并对符合《精神疾病诊断与统计手册》第三版修订版(DSM-III-R)酒精依赖标准(303.90)的患者进行这些项目的评定。根据自上次饮酒以来经过的时间长短将患者分为两组。这两组分别称为早期戒断组(n = 53),在1周内每天进行评定,以及晚期戒断组(n = 13),在7周内每周评定一次。为了证明纳入新量表的合理性,项目必须要么在至少一半的戒断组患者中显示出精神病理学表现,要么在0.1%的显著性水平上对随时间的变化敏感。有17个项目符合这些标准之一。在一个新的早期戒断患者样本(n = 30)中对该量表进行了评定者间信度测试。评定者间信度以及内部一致性均令人满意。这种能够识别精神病理学及随时间变化情况的新量表,可以单独使用或与生理量表一起使用,以识别正在经历戒断的患者亚组。