睡眠期间空气中螨虫过敏原（Der I和Der II）的浓度。

Concentration of airborne mite allergens (Der I and Der II) during sleep.

作者信息

Sakaguchi M, Inouye S, Yasueda H, Shida T

机构信息

Department of Microbiology, Institute of Public Health, Tokyo, Japan.

出版信息

Allergy. 1992 Feb;47(1):55-7. doi: 10.1111/j.1398-9995.1992.tb02250.x.

DOI:10.1111/j.1398-9995.1992.tb02250.x

PMID:1590568

Abstract

Using a low-noise air sampler and a sensitive radioimmunoassay, we measured the concentration of mite allergens in the air during sleeping with Japanese bedquilts (futon). The airborne allergen levels of Der I (Der p I plus Der f I) and Der II during sleep were 223 and 87.1 pg/m3 of air, respectively. These levels were about 10-fold higher than those during usual domestic life in the living room of the same houses. When the bedquilts were changed to new ones free of mite allergens, the airborne allergen levels of Der I and Der II were decreased to 11.5 and 12.0 pg/m3, respectively. This indicated that the mite airborne allergens during sleep were generated from the used bedding, not from the floor. We believe that exposure to airborne mite allergens during sleep might be an important factor in the development of mite allergies.

摘要

我们使用低噪音空气采样器和灵敏的放射免疫分析法，测量了使用日式棉被（蒲团）睡觉时空气中螨虫过敏原的浓度。睡眠期间空气中Der I（Der p I加Der f I）和Der II的过敏原水平分别为每立方米空气223皮克和87.1皮克。这些水平比同一房屋客厅正常家居生活期间的水平高出约10倍。当棉被换成不含螨虫过敏原的新棉被时，Der I和Der II的空气中过敏原水平分别降至11.5皮克/立方米和12.0皮克/立方米。这表明睡眠期间空气中的螨虫过敏原是由用过的床上用品产生的，而非来自地板。我们认为睡眠期间暴露于空气中的螨虫过敏原可能是螨虫过敏发生的一个重要因素。