Kouri Vivian, Liang Xiaozhen, Rodriguez Maria Elena, Capo Virginia, Resik Sonia, Barrios Julio, Mantecon Beatriz, Blanco Orestes, Means Robert, Jung Jae U, Lee Bok-Soo, Hengge Ulrich R
Department of Virology, Institute of Tropical Medicine Pedro Kouri, Havana City, Cuba.
AIDS. 2005 Jun 10;19(9):984-7. doi: 10.1097/01.aids.0000171416.07034.d6.
Kaposi's sarcoma-associated herpesvirus (KSHV) is detected consistently in Kaposi's sarcoma (KS). Because of its dramatic sequence variation, the K1 gene has been used to classify KSHV. We found a diverse array of KSHV subtypes A1, A2, A3, A5, B1, B2, and C3 in 23 Cuban KS samples containing several novel sporadic insertions/deletions in subtypes A and C. The molecular epidemiology of the KSHV subtypes seems to reflect the unique mixed ethnic background of the Cuban population.
卡波西肉瘤相关疱疹病毒（KSHV）在卡波西肉瘤（KS）中一直被检测到。由于其显著的序列变异，K1基因已被用于对KSHV进行分类。我们在23份古巴KS样本中发现了多种KSHV亚型，即A1、A2、A3、A5、B1、B2和C3，其中A和C亚型含有几个新的散发性插入/缺失。KSHV亚型的分子流行病学似乎反映了古巴人群独特的混合种族背景。
