Lehmkuhl L A A, Park S, Zakutansky D, Jastremski C A, Wallace J P
Forschungsbereich Sport- und Bewegungsmedizin, Fachbereich Sportwissenschaft, Universität Hamburg, Hamburg, Germany.
J Hum Hypertens. 2005 Aug;19(8):589-95. doi: 10.1038/sj.jhh.1001848.
The accuracy and reproducibility of ambulatory blood pressure monitoring used in intervention and treatment studies is essential to assure the desired health outcomes. The reproducibility of ambulatory variables in pharmacological studies has been reported, however, the reproducibility of ambulatory blood pressure variables associated with exercise has not been reported. Thus, the purpose of this study was to investigate the reproducibility of the postexercise ambulatory blood pressure in Stage I hypertensive adults. It was hypothesized that the reproducibility of the ambulatory blood pressure variables would not be different following two corresponding exercise and control treatments. A total of 18 Stage I hypertensive adults (142.1+/-3.15/91.6+/-1.80 mmHg) performed four randomized, 24 h AmBP monitoring sessions: two following a 50 min treadmill walk (50% VO(2) peak) and two on control days. Variables measured were: (1) average systolic and diastolic pressures for 24 h, daytime (06:00-22:00 h) and night time (22:00-06:00 h) and (2) systolic and diastolic load for the same time periods. Both a nonsignificant paired t-test and an excellent intraclass correlation were used to define reproducibility of the variables between the 1st and 2nd exercise trials and between the 1st and 2nd control trials. Reproducibility was found for all the control variables except for nighttime diastolic load. Reproducibility was found for all the systolic and diastolic exercise variables. Ambulatory blood pressure measurements, including average systolic and diastolic blood pressures and systolic and diastolic loads for 24 h, daytime and night time periods are reproducible following exercise.
在干预和治疗研究中使用的动态血压监测的准确性和可重复性对于确保期望的健康结果至关重要。药物研究中动态变量的可重复性已有报道，然而，与运动相关的动态血压变量的可重复性尚未见报道。因此，本研究的目的是调查I期高血压成年人运动后动态血压的可重复性。研究假设是，在两次相应的运动和对照治疗后，动态血压变量的可重复性不会有差异。共有18名I期高血压成年人（收缩压142.1±3.15/舒张压91.6±1.80 mmHg）进行了四次随机的24小时动态血压监测：两次在进行50分钟跑步机行走（50%最大摄氧量峰值）后，两次在对照日。测量的变量包括：（1）24小时、白天（06:00 - 22:00）和夜间（22:00 - 06:00）的平均收缩压和舒张压，以及（2）相同时间段的收缩压和舒张压负荷。使用无显著差异的配对t检验和良好的组内相关性来定义第一次和第二次运动试验之间以及第一次和第二次对照试验之间变量的可重复性。除夜间舒张压负荷外，所有对照变量均具有可重复性。所有收缩压和舒张压运动变量均具有可重复性。运动后，包括24小时、白天和夜间的平均收缩压和舒张压以及收缩压和舒张压负荷在内的动态血压测量具有可重复性。
