Cronemberger Sebastião, Calixto Nassim, Costa Leonardo Torqueti, Soares Fábio Martins
Serviço de Glaucoma, Hospital São Geraldo, MG.
Arq Bras Oftalmol. 2005 Mar-Apr;68(2):185-8. doi: 10.1590/s0004-27492005000200006. Epub 2005 May 18.
To evaluate in suspected and glaucomatous patients the correlation between central corneal thickness (CCT) and intraocular pressure (IOP), measured during the daily curve of intraocular pressure (DCPo), including CCT and IOP measurements in bed at 6 am. The ocular axial length was also compared.
114 eyes from 73 patients, 30 eyes suspected of glaucoma (group I) and 84 eyes with chronic open-angle glaucoma (group II) were prospectively studied. Both groups were subjected to DCPo with measurements of IOP at 9 am, 12 pm, 6 pm, 10:30 pm and on the next day at 6 am in bed and in darkness before the patient gets up. Using the ultrasonic DGH 5100 device, CCT measurements were performed at 9 am, 6 pm, 10:30 pm and the next day at 6 am in bed before the patient gets up. The ocular axial length was also measured.
In the total sample and, separately in each group, the mean IOP was more elevated in bed at 6 am. There were no significant CCT changes during the day within each group or between both groups. No statistically significant difference was found between the mean ocular axial length of both groups.
In suspected and glaucomatous patients, there were no statistically significant CCT variations during the day; therefore, only one CCT measurement is sufficient. Also, there was no statistically significant difference between ocular axial length of both groups.
评估疑似青光眼患者和青光眼患者的中央角膜厚度（CCT）与眼内压（IOP）之间的相关性，IOP测量在眼内压日曲线（DCPo）期间进行，包括上午6点卧床时的CCT和IOP测量。同时比较眼轴长度。
前瞻性研究了73例患者的114只眼，其中30只眼疑似青光眼（I组），84只眼患有慢性开角型青光眼（II组）。两组均接受DCPo检查，分别于上午9点、中午12点、下午6点、晚上10:30以及次日上午6点患者起床前在黑暗中卧床时测量IOP。使用超声DGH 5100设备，分别于上午9点、下午6点、晚上10:30以及次日上午6点患者起床前在卧床时测量CCT。同时测量眼轴长度。
在整个样本以及每组中，上午6点卧床时的平均IOP更高。每组内及两组之间白天的CCT均无显著变化。两组的平均眼轴长度之间未发现统计学上的显著差异。
在疑似青光眼患者和青光眼患者中，白天CCT无统计学上的显著变化；因此，仅一次CCT测量就足够了。此外，两组的眼轴长度之间也没有统计学上的显著差异。
