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[眼球摘除术和眼内容剜出术后兔眼眶测量评估]

[Rabbit orbital measure evaluations after enucleation and evisceration].

作者信息

Shiratori Claudia Akemi, Schellini Silvana Artioli, Yamashita Seizo, Padovani Carlos Roberto, Rossa Romualdo

机构信息

Faculdade de Medicina de Botucatu, UNESP, Botucatu, SP.

出版信息

Arq Bras Oftalmol. 2005 Mar-Apr;68(2):235-9. doi: 10.1590/s0004-27492005000200015. Epub 2005 May 18.

DOI:10.1590/s0004-27492005000200015
PMID:15905947
Abstract

PURPOSE

To assess orbital volume in weaned rabbits, submitted to enucleation and evisceration, with orbital volume reconstitution using porous polyethylene (PP) spheres, analyzed by computed tomography, by the water displacement test and external orbital measures using Image-J software.

METHODS

This experimental randomized study consisted of 48 albino rabbits, with 42 days of life, submitted to enucleation (EN) and evisceration (EV), with (WI) or without (NI) implantation of a 10 mm PP sphere. After 1 month (M1), 3 months (M2) and 6 months (M3), 4 animals of each group were sacrificed. The skulls were prepared for dry bone study using the maceration technique. The orbital volume was calculated by computed tomography and by the water displacement test. The results suggest that orbital development in rabbits above 42 days of life is not different regarding evisceration or enucleation, or when an orbital implant is used. The water displacement test showed similar results compared with computed tomography, making a morphometric method in experimental studies worthwhile.

摘要

目的

通过计算机断层扫描、水置换试验以及使用Image-J软件进行眼眶外部测量,评估断奶后接受眼球摘除术和眼内容剜出术的兔子眼眶体积,并用多孔聚乙烯(PP)球进行眼眶体积重建。

方法

本实验性随机研究包括48只42日龄的白化兔,接受眼球摘除术(EN)和眼内容剜出术(EV),植入(WI)或不植入(NI)10毫米PP球。在1个月(M1)、3个月(M2)和6个月(M3)后,每组处死4只动物。使用浸渍技术制备颅骨用于干骨研究。通过计算机断层扫描和水置换试验计算眼眶体积。结果表明,42日龄以上兔子的眼眶发育在眼内容剜出术或眼球摘除术方面没有差异,使用眼眶植入物时也没有差异。水置换试验与计算机断层扫描结果相似,这使得形态测量方法在实验研究中具有价值。

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