Kothe C, Schade G, Fleischer S, Grundmann T, Hess M
Klinik und Poliklinik für Hals-, Nasen- und Ohrenheilkunde, Universitätsklinikum Hamburg-Eppendorf, 20246 Hamburg.
HNO. 2005 Jul;53(7):651-4. doi: 10.1007/s00106-005-1270-x.
Laryngeal edema is considered a postoperative problem in phonosurgery. In a prospective study we examined if a single intraoperative application of prednisolone can decrease the incidence of postoperative laryngeal edema after Isshiki type I thyroplasty. We examined ten patients undergoing unilateral type I thyroplasty [seven men and three women, age range: 19-60 years (average: 48 years)]. In six patients we administered 250 mg prednisolone i.v. during surgery. In four patients no steroids were given at all. On the 1st and 2nd postoperative day, the larynx was examined in a clinical setting. Five of six patients who received intraoperative steroid medication had no postoperative laryngeal edema. Only in one of those patients we examined a small edema of the arytenoid region. In all four patients without steroid medication a postoperative edema of the ipsilateral arytenoid hump was seen. Thus, intraoperative intravenous steroid administration seems to prevent, or at least reduce, postoperative laryngeal edema. Only in one of those patients we examined a small edema of the arytenoid region.
喉水肿被认为是嗓音外科手术后的一个问题。在一项前瞻性研究中，我们检查了术中单次应用泼尼松龙是否能降低石木I型甲状成形术后喉水肿的发生率。我们检查了10例行单侧I型甲状成形术的患者[7名男性和3名女性，年龄范围：19 - 60岁（平均：48岁）]。6例患者在手术期间静脉注射250 mg泼尼松龙。4例患者完全未给予类固醇。在术后第1天和第2天，在临床环境中检查喉部。接受术中类固醇药物治疗的6例患者中有5例没有术后喉水肿。仅在其中1例患者中，我们检查到杓状软骨区域有轻微水肿。在所有4例未使用类固醇药物的患者中，均可见同侧杓状隆突术后水肿。因此，术中静脉注射类固醇似乎可以预防或至少减轻术后喉水肿。仅在其中1例患者中，我们检查到杓状软骨区域有轻微水肿。
