全肺实质的T1映射：呼吸相位对健康个体的影响。
T1 mapping of the entire lung parenchyma: Influence of the respiratory phase in healthy individuals.
作者信息
Stadler Alfred, Jakob Peter M, Griswold Mark, Barth Markus, Bankier Alexander A
机构信息
Department of Radiology, Medical University of Vienna, Vienna, Austria.
出版信息
J Magn Reson Imaging. 2005 Jun;21(6):759-64. doi: 10.1002/jmri.20319.
PURPOSE
To determine the effect of respiratory phase on the T1 values of the entire lung.
MATERIALS AND METHODS
We calculated T1 relaxation time on a pixel-by-pixel analysis of a series of Snapshot FLASH tomograms acquired after a single inversion pulse. Two sets of coronal T1 maps were acquired, one in full suspended inspiration and one in suspended expiration.
RESULTS
The average of the mean T1 values over the entire lung in inspiration was 1199+/-117 msec, the average of the mean T1 values in expiration was 1333+/-167 msec. This difference was statistically significant, at P=0.005. In inspiration the average coefficient of variation was 182+/-56 msec, in expiration it was 153+/-41 msec. This difference was not statistically significant.
CONCLUSION
T1 measurements of the entire lung are feasible. Our findings underline the need for a close monitoring of the inspirational status during MR examinations of the thorax, notably when T1 measurements of the lung are performed.
目的
确定呼吸相位对全肺T1值的影响。
材料与方法
我们在对单次反转脉冲后采集的一系列快速小角度激发（Snapshot FLASH）断层图像进行逐像素分析时计算T1弛豫时间。采集了两组冠状面T1图，一组在完全屏气吸气时采集，另一组在屏气呼气时采集。
结果
吸气时全肺平均T1值的平均值为1199±117毫秒，呼气时平均T1值的平均值为1333±167毫秒。此差异具有统计学意义，P = 0.005。吸气时平均变异系数为182±56毫秒，呼气时为153±41毫秒。此差异无统计学意义。
结论
全肺T1测量是可行的。我们的研究结果强调在胸部磁共振检查期间，尤其是进行肺部T1测量时，需要密切监测呼吸状态。
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