Erdem Guliz, Ford Jacqueline M, Kanenaka Rebecca Y, Abe Lucienne, Yamaga Karen, Effler Paul V
John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96826, USA.
Clin Infect Dis. 2005 Jun 15;40(12):1851-4. doi: 10.1086/430378. Epub 2005 May 9.
Two clusters of necrotizing fasciitis (NF) due to group A streptococcus (GAS) were identified on the Hawaiian islands of Kauai and Maui during 1997 and 2002, respectively. The emm gene sequence types and the pulsed-field gel electrophoresis patterns were determined for 6 isolates recovered from patients with NF and for 116 isolates recovered from patients with temporally associated community-acquired GAS infection. No predominant emm type was identified, and the emm types of 64 (52.5%) of the isolates were considered to be uncommon in the continental United States. These findings suggest that unusual emm types might be responsible for invasive GAS infections in patients from Hawaii.
1997年和2002年，在夏威夷考艾岛和毛伊岛分别发现了两起因A组链球菌（GAS）引起的坏死性筋膜炎（NF）病例群。对从坏死性筋膜炎患者中分离出的6株菌株以及从时间上与之相关的社区获得性GAS感染患者中分离出的116株菌株，测定了其emm基因序列类型和脉冲场凝胶电泳图谱。未发现占主导地位的emm型，其中64株（52.5%）菌株的emm型在美国大陆被认为不常见。这些发现表明，不常见的emm型可能是导致夏威夷患者侵袭性GAS感染的原因。
