De Smet J, Gzil P, Vervoort N, Verelst H, Baron G V, Desmet G
Department of Chemical Engineering, Vrije Universiteit Brussel, Pleinlaan 2, 1050 Brussels, Belgium.
J Chromatogr A. 2005 May 6;1073(1-2):43-51. doi: 10.1016/j.chroma.2004.10.008.
We report on a theoretical study wherein we considered a large number of ordered two-dimensional porous pillar arrays with different pillar shapes and widely varying external porosity and calculated the flow resistance and the band broadening (under retentive conditions) over the complete range of practical velocities using a commercial computational fluid dynamics software package. It is found that the performance of the small porosity systems is very sensitive to the exact pillar shape, whereas this difference gradually disappears with increasing porosity. The obtained separation impedances are very small in comparison to packed bed and monolithic columns and decrease with increasing porosity. If accounting for the current micromachining limitations, a proper selection of the exact shape and porosity even becomes more critical, and different design rules are obtained depending on whether porous or non-porous pillars are considered.
我们报告了一项理论研究，其中我们考虑了大量具有不同柱体形状以及广泛变化的外部孔隙率的有序二维多孔柱阵列，并使用商业计算流体动力学软件包在实际速度的整个范围内计算了流动阻力和（在保留条件下的）谱带展宽。结果发现，小孔隙率系统的性能对柱体的确切形状非常敏感，而随着孔隙率增加这种差异逐渐消失。与填充床和整体柱相比，所获得的分离阻抗非常小，并且随着孔隙率增加而降低。如果考虑当前微加工的限制，柱体的确切形状和孔隙率的适当选择甚至变得更加关键，并且根据是否考虑多孔或无孔柱体可获得不同的设计规则。
