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肺和胸膜原发性血管肉瘤

Primary angiosarcoma of the lung and pleura.

作者信息

Maglaras G C, Katsenos S, Kakadelis J, Katsanos C, Metafratzi Z, Stefanou D G, Vassiliou M P, Constantopoulos S H

机构信息

Department of Pneumonology, University Hospital of Ioannina, Greece.

出版信息

Monaldi Arch Chest Dis. 2004 Oct-Dec;61(4):234-6. doi: 10.4081/monaldi.2004.687.

DOI:10.4081/monaldi.2004.687
PMID:15909614
Abstract

A 46 year old male smoker was admitted for severe continuing hemoptysis. Chest-X-rays and chest computed tomography revealed nodular infiltrates and bilateral hemothorax. Fiberoptic bronchoscopy resulted to non-diagnostic cytological and microbiological findings. Open lung and pleural biopsies after right thoracotomy revealed epithelioid angiosarcoma and further staging assessment showed secondary brain and liver foci. The patient received several courses of chemotherapy but he died one month later. The clinical, radiological, pathological, histochemical and therapeutic aspects of the disease are discussed. Angiosarcoma, a rare tumour with poor prognosis should be taken into consideration in the differential diagnosis of hemoptysis.

摘要

一名46岁男性吸烟者因严重持续咯血入院。胸部X光片和胸部计算机断层扫描显示结节状浸润和双侧血胸。纤维支气管镜检查的细胞学和微生物学检查结果未明确诊断。右胸开胸肺和胸膜活检显示上皮样血管肉瘤,进一步分期评估显示继发性脑和肝转移灶。患者接受了几个疗程的化疗,但一个月后死亡。本文讨论了该疾病的临床、放射学、病理学、组织化学和治疗方面。血管肉瘤是一种预后不良的罕见肿瘤,在咯血的鉴别诊断中应予以考虑。

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