Mirsaeidi S M, Tabarsi P, Edrissian M O, Amiri M, Farnia P, Mansouri S D, Masjedi M R, Velayati A A
National Research Institute of Tuberculosis and Lung Diseases, Shaheed Beheshti University of Medical Sciences, Tehran, Iran.
Monaldi Arch Chest Dis. 2004 Oct-Dec;61(4):244-7. doi: 10.4081/monaldi.2004.690.
Primary multi-drug resistant extrapulmonary tuberculosis is an uncommon form of the disease, but it seems that by increasing the number drug resistant tuberculosis around the world, the number of cases of primary multi-drug resistant tuberculosis with extrapulmonary presentation also is going to rise. In this report, we describe a 19-year old, HIV negative man with primary multi-drug resistant TB lymphadenitis, presented with cervical lymphadenopathy and sinus discharge at the site of involved lymph nodes. The Acid Fast Bacilli (AFB) smear of sputum was negative but the AFB smear of discharged fluid as well as the excisional biopsy of the lymph nodes confirmed the M. tuberculosis infection. The patient underwent the treatment with a combination of isoniazide, clofazimine, pyrazinamide, ofloxacin and amikacin with promising results. By increasing the number of drug resistant tuberculosis patients around the world, appropriate diagnosis and treatment of different presentations of the disease need a special attention.
原发性耐多药肺外结核病是一种不常见的疾病形式，但随着全球耐多药结核病病例数量的增加，原发性耐多药肺外结核病的病例数似乎也会上升。在本报告中，我们描述了一名19岁、HIV阴性的男性，患有原发性耐多药结核性淋巴结炎，表现为颈部淋巴结病及受累淋巴结部位的窦道排液。痰涂片抗酸杆菌（AFB）阴性，但排出液涂片及淋巴结切除活检证实为结核分枝杆菌感染。该患者接受了异烟肼、氯法齐明、吡嗪酰胺、氧氟沙星和阿米卡星联合治疗，效果良好。随着全球耐多药结核病患者数量的增加，对该疾病不同表现形式的正确诊断和治疗需要特别关注。
