Yang Huei-Chen, Sheu Ming-Huei, Wang Jia-Hwia, Chang Cheng-Yen
Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan.
Kaohsiung J Med Sci. 2005 Apr;21(4):153-8. doi: 10.1016/S1607-551X(09)70294-3.
The purpose of this study was to compare the efficacy of two laxatives, castor oil and bisacodyl, in the routine bowel preparation of outpatients for intravenous urography (IVU). We used castor oil in patients undergoing IVU for 1 month, and then used bisacodyl in patients undergoing IVU for another month. Two uroradiologists, unaware of the method of bowel preparation, reviewed the standard radiographs and graded the residue in the large bowel and the clearness of the opacified urinary collecting system. In total, 71 consecutive outpatients received castor oil, and 84 received bisacodyl. For the castor oil group, grades from the two uroradiologists did not differ in terms of fecal residue on plain abdominal images (p = 0.54), and visualization of the urinary system on the left (p = 0.36) and right sides (p = 0.63). Findings were similar for bisacodyl recipients (p = 0.11, 0.59, and 0.32, respectively). When the laxative effect of the two agents was compared, we found no difference in the grading of fecal residue on plain abdominal images (p = 0.14), or in visualization of the urinary system on the left (p = 0.31) and right sides (p = 0.98). In conclusion, we observed no difference in laxative efficacy between castor oil and bisacodyl; thus, bisacodyl may be a useful alternative for bowel preparation before IVU.
本研究的目的是比较两种泻药蓖麻油和比沙可啶在门诊患者静脉尿路造影(IVU)常规肠道准备中的效果。我们让接受IVU的患者使用蓖麻油1个月,然后让另一组接受IVU的患者使用比沙可啶1个月。两位泌尿放射科医生在不知道肠道准备方法的情况下,查看了标准X光片,并对大肠内的残留物以及显影的泌尿系统的清晰度进行了分级。共有71名连续的门诊患者使用了蓖麻油,84名患者使用了比沙可啶。对于蓖麻油组,两位泌尿放射科医生在腹部平片上的粪便残留分级方面没有差异(p = 0.54),在左侧(p = 0.36)和右侧(p = 0.63)泌尿系统的显影方面也没有差异。比沙可啶使用者的结果类似(分别为p = 0.11、0.59和0.32)。当比较两种药物的泻药效果时,我们发现在腹部平片上的粪便残留分级方面没有差异(p = 0.14),在左侧(p = 0.31)和右侧(p = 0.98)泌尿系统的显影方面也没有差异。总之,我们观察到蓖麻油和比沙可啶在泻药效果上没有差异;因此,比沙可啶可能是IVU前肠道准备的一种有用替代药物。