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阿米卡星与黏菌素治疗鲍曼不动杆菌脑膜炎

Amikacin and colistin for treatment of Acinetobacter baumannii meningitis.

作者信息

Fulnecky Eric J, Wright Donald, Scheld W Michael, Kanawati Lama, Shoham Shmuel

机构信息

Section of Infectious Diseases, Washington Hospital Center, 110 Irving Street, Washington, DC 20010, USA.

出版信息

J Infect. 2005 Dec;51(5):e249-51. doi: 10.1016/j.jinf.2005.04.003.

DOI:10.1016/j.jinf.2005.04.003
PMID:15913780
Abstract

We report a case of a 52-year-old man with post-surgical meningitis due to a multi-drug resistant Acinetobacter baumannii. Despite therapy with intravenous amikacin and imipenem the meningitis progressed. Upon institution of combination therapy with amikacin by the intravenous and intrathecal (IT) routes, and intravenous colistin the patient experienced successful clinical and microbiological outcomes.

摘要

我们报告一例52岁男性患者,因多重耐药鲍曼不动杆菌导致术后脑膜炎。尽管使用静脉注射阿米卡星和亚胺培南进行治疗,脑膜炎仍进展。在采用静脉和鞘内(IT)途径联合使用阿米卡星以及静脉注射多粘菌素进行治疗后,患者获得了成功的临床和微生物学结果。

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Amikacin and colistin for treatment of Acinetobacter baumannii meningitis.阿米卡星与黏菌素治疗鲍曼不动杆菌脑膜炎
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