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[塞内加尔的放线菌性足菌肿:90例病例研究]

[Actinomycetomas in Senegal: study of 90 cases].

作者信息

Dieng M T, Niang S O, Diop B, Ndiaye B

机构信息

Service de dermatologie, CHU Le Dantec, BP 3001, Dakar, Sénégal.

出版信息

Bull Soc Pathol Exot. 2005 Apr;98(1):18-20.

Abstract

Mycetoma is a pathological process during which eumycetomic (fungal) or actinomycotic causative agents from exogenous source produce grains. Medical treatment is available for actinomycetomas and surgery is still the main treatment for eumycetoma. We report 90 cases of actinomycetoma occuring in male adult patients coming mainly from central Senegal. Patients living far from health structures consult after a long evolution period for tumors and pains which prevent them from carrying out their activities. The three etiological agents in our patients were Actinomadura pelletieri (60 cases), Actinomadura madurae (25 cases) and Streptomyces somaliensis (5 cases). The three clinical features are inflammatory forms (75 cases) mainly due to Actinomadura pelletieri, tumoral forms (13 cases) and cystic forms (2 cases). Lesions are localized on the foot in 50% of cases and in other part of the body for the other half. Bone damage was observed in 55% of cases. 83% of the patients were cured after a one-year treatment of sulfametoxazole adminstered orally. Two patients died of visceral involvement.

摘要

足菌肿是一种病理过程,在此过程中,来自外源的真菌性(真菌)或放线菌性病原体产生颗粒。放线菌性足菌肿可进行药物治疗,而手术仍是真菌性足菌肿的主要治疗方法。我们报告了90例主要发生在塞内加尔中部成年男性患者中的放线菌性足菌肿病例。居住在远离医疗结构地区的患者在肿瘤和疼痛长期发展后才前来咨询,这些症状使他们无法正常活动。我们患者中的三种病原体分别是佩氏马杜拉放线菌(60例)、马杜拉马杜拉放线菌(25例)和索马里链霉菌(5例)。三种临床特征为炎症型(75例),主要由佩氏马杜拉放线菌引起,肿瘤型(13例)和囊肿型(2例)。50%的病例病变位于足部,另一半位于身体其他部位。55%的病例观察到骨损伤。83%的患者在口服磺胺甲恶唑一年治疗后治愈。两名患者死于内脏受累。

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