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医院层面产科质量指标与孕产妇及新生儿发病率之间的关联

Association between hospital-level obstetric quality indicators and maternal and neonatal morbidity.

作者信息

Howell Elizabeth A, Zeitlin Jennifer, Hebert Paul L, Balbierz Amy, Egorova Natalia

机构信息

Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York2Department of Obstetrics, Gynecology, and Reproductive Science, Icahn School of Medicine at Mount Sinai, New York, New York.

Department of Population Health Science & Policy, Icahn School of Medicine at Mount Sinai, New York, New York3Inserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Biostatistics Sorbonne Pari.

出版信息

JAMA. 2014 Oct 15;312(15):1531-41. doi: 10.1001/jama.2014.13381.

Abstract

IMPORTANCE

In an effort to improve the quality of care, several obstetric-specific quality measures are now monitored and publicly reported. The extent to which these measures are associated with maternal and neonatal morbidity is not known.

OBJECTIVE

To examine whether 2 Joint Commission obstetric quality indicators are associated with maternal and neonatal morbidity.

DESIGN, SETTING, AND PARTICIPANTS: Population-based observational study using linked New York City discharge and birth certificate data sets from 2010. All delivery hospitalizations were identified and 2 perinatal quality measures were calculated (elective, nonmedically indicated deliveries at 37 or more weeks of gestation and before 39 weeks of gestation; cesarean delivery performed in low-risk mothers). Published algorithms were used to identify severe maternal morbidity (delivery associated with a life-threatening complication or performance of a lifesaving procedure) and morbidity in term newborns without anomalies (births associated with complications such as birth trauma, hypoxia, and prolonged length of stay). Mixed-effects logistic regression models were used to examine the association between maternal morbidity, neonatal morbidity, and hospital-level quality measures while risk-adjusting for patient sociodemographic and clinical characteristics.

MAIN OUTCOMES AND MEASURES

Individual- and hospital-level maternal and neonatal morbidity.

RESULTS

Severe maternal morbidity occurred among 2372 of 115,742 deliveries (2.4%), and neonatal morbidity occurred among 8057 of 103,416 term newborns without anomalies (7.8%). Rates for elective deliveries performed before 39 weeks of gestation ranged from 15.5 to 41.9 per 100 deliveries among 41 hospitals. There were 11.7 to 39.3 cesarean deliveries per 100 deliveries performed in low-risk mothers. Maternal morbidity ranged from 0.9 to 5.7 mothers with complications per 100 deliveries and neonatal morbidity from 3.1 to 21.3 neonates with complications per 100 births. The maternal quality indicators elective delivery before 39 weeks of gestation and cesarean delivery performed in low-risk mothers were not associated with severe maternal complications (risk ratio [RR], 1.00 [95% CI, 0.98-1.02] and RR, 0.99 [95% CI, 0.96-1.01], respectively) or neonatal morbidity (RR, 0.99 [95% CI, 0.97-1.01] and RR, 1.01 [95% CI, 0.99-1.03], respectively).

CONCLUSIONS AND RELEVANCE

Rates for the quality indicators elective delivery before 39 weeks of gestation and cesarean delivery performed in low-risk mothers varied widely in New York City hospitals, as did rates of maternal and neonatal complications. However, there were no correlations between the quality indicator rates and maternal and neonatal morbidity. Current quality indicators may not be sufficiently comprehensive for guiding quality improvement in obstetric care.

摘要

重要性

为提高医疗质量,目前对多项产科特定质量指标进行监测并公开报告。但这些指标与孕产妇和新生儿发病率之间的关联程度尚不清楚。

目的

探讨联合委员会的两项产科质量指标是否与孕产妇和新生儿发病率相关。

设计、地点和参与者:基于人群的观察性研究,使用2010年纽约市出院数据与出生证明数据集相链接的数据。识别出所有分娩住院病例,并计算两项围产期质量指标(妊娠37周及以上且在39周之前的择期、非医学指征分娩;低风险母亲进行剖宫产)。使用已发表的算法识别严重孕产妇发病率(与危及生命的并发症相关的分娩或进行挽救生命的手术)以及足月无异常新生儿的发病率(与出生创伤、缺氧和住院时间延长等并发症相关的出生)。使用混合效应逻辑回归模型来检验孕产妇发病率、新生儿发病率与医院层面质量指标之间关联,同时对患者社会人口统计学和临床特征进行风险调整。

主要结局和指标

个体及医院层面的孕产妇和新生儿发病率。

结果

115742例分娩中有2372例发生严重孕产妇发病率(2.4%),103416例足月无异常新生儿中有8057例发生新生儿发病率(7.8%)。41家医院中,妊娠39周之前的择期分娩率为每100例分娩15.5至41.9例。低风险母亲每100例分娩中有11.7至39.3例剖宫产。孕产妇发病率为每100例分娩中有0.9至5.7例有并发症的母亲,新生儿发病率为每100例出生中有3.1至21.3例有并发症的新生儿。孕产妇质量指标妊娠39周之前的择期分娩和低风险母亲进行剖宫产与严重孕产妇并发症(风险比[RR]分别为1.00[95%置信区间,0.98 - 1.02]和RR为0.99[95%置信区间,0.96 - 1.01])或新生儿发病率(RR分别为0.99[95%置信区间,0.97 - 1.01]和RR为1.01[95%置信区间,0.99 - 1.03])均无关联。

结论及意义

纽约市各医院中,妊娠39周之前的择期分娩和低风险母亲进行剖宫产这两项质量指标的发生率差异很大,孕产妇和新生儿并发症发生率也是如此。然而,质量指标发生率与孕产妇和新生儿发病率之间没有相关性。当前的质量指标可能不够全面,不足以指导产科护理质量的改善。

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